Results 251 to 260 of about 6,486,745 (293)
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The effect of para-chlorophenylalanine on spontaneous locomotor activity in the rat
Neuropharmacology, 1971Abstract The effect of p-chlorophenylalanine (p-CPA), a depletor of serotonin, on spontaneous locomotor activity was investigated in rats. It was found that p-CPA induced large and reproducible increases in locomotor activity in a variety of situations. This hyperactivity could be reversed by 5-hydroxytryptophan, a precursor of serotonin.
H C, Fibiger, B A, Campbell
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Opiate control of spontaneous locomotor activity in a urodele amphibian
Pharmacology Biochemistry and Behavior, 1989An intraperitoneal injection of the preferential opiate receptor agonist (+/-) bremazocine HCl given to male rough-skinned newts acutely and dose-dependently reduced their spontaneous locomotor activity. Inversely, and contrary to the situation generally observed in other vertebrates, administration of the opiate receptor antagonist naloxone HCl dose ...
P, Deviche, C A, Lowry, F L, Moore
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The spontaneous locomotor activity of young, middle-aged and old Drosophila melanogaster of both sexes has been videorecorded during three parabolic flights separated by one-day intervals. Fast shifts between 0 g, 1 g and 1.8 g phases are obtained during
Eric Le Bourg, F A Lints
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Brain Histamine: Plasma Corticosterone, Spontaneous Locomotor Activity and Temperature
Pharmacology Biochemistry and Behavior, 1980Hypothalamic histamine exhibited circadian fluctuations in male Sprague-Dawley rats; low values were found during the dark period when spontaneous locomotor activity (S.L.A.) and temperature were elevated. A relatively high hypothalamic histamine level was observed during the early period of the light cycle and was associated with decreased S.L.A.
I M Mazurkiewicz-Kwilecki +1 more
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Naltrexone fails to suppress spontaneous locomotor activity in hamsters
Pharmacology Biochemistry and Behavior, 1985The increased spontaneous locomotor activity (SLMA) of rats exposed to a novel environment is decreased by opiate antagonists. In the present study, naltrexone (1.0-40 mg/kg) failed to reduce the SLMA of hamsters exposed to the novel environment of activity cages.
M T, Lowy, S, Sangiah, G K, Yim
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Righting reflexes and spontaneous locomotor activity during hypothermia
Cryobiology, 1969Summary Righting reflexes were tested, and spontaneous locomotor activity was measured in unanesthetized small mammals during the induction of progressive hypothermia. The body-on-body-righting reflex was lost by the guinea pig at a body temperature of 29.2 ± 0.8 (S.
J A, Panuska +2 more
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Hypoxia and Spontaneous Locomotor Activity in the Rat
Perceptual and Motor Skills, 1967Three experiments investigated the effects of hypoxia on activity wheel running in male Sprague-Dawley rats. Ss were exposed to atmospheres containing 21% O 2 (normoxia), 16% O 2 , 12% O 2 , and 8% O
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Effects of Chlorogenic Acid and Its Metabolites on Spontaneous Locomotor Activity in Mice. [PDF]
Chlorogenic acid possessed a weak caffeine-like psychostimulant property when assessed for its effect on spontaneous locomotor activity in mice. In the evaluation of the effects for the major metabolites of chlorogenic acid which were detected upon incubation with rat feces and/or excreted in urine after oral administration to rats, caffeic and m ...
Takashi Yoshida +2 more
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The effects of tricyclic and ‘atypical’ antidepressants on spontaneous locomotor activity in rodents
Neuroscience & Biobehavioral Reviews, 1986With the exception of amineptin, buproprion and nomifensine all tricyclic and 'atypical' antidepressants have been reported to reduce spontaneous motor activity in rodents, after both acute and chronic administration. However, with the diversity of chemical actions of these drugs it is unlikely that a single neurochemical mechanism is underlying this ...
J C, Tucker, S E, File
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Effects of atomoxetine on locomotor activity and impulsivity in the spontaneously hypertensive rat
Behavioural Brain Research, 2013Atomoxetine (ATX) is a commonly used non-stimulant treatment for Attention deficit hyperactivity disorder (ADHD). It primarily acts to increase noradrenalin levels; however, at higher doses it can increase dopamine levels. To date there has been no investigations into the effects of orally-administered ATX in the most commonly used model of ADHD, the ...
Turner, Michael +3 more
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