Results 31 to 40 of about 9,929,291 (244)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Utilising Spontaneous Conversational Speech in HMM-Based Speech Synthesis [PDF]
, 2010 Spontaneous conversational speech has many characteristics that are currently not well modelled in unit selection and HMM-based speech synthesis. But in order to build synthetic voices more suitable for interaction we need data that exhibits more ...
Clark, Robert +2 more
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The Meaning of Spontaneous Symmetry Breaking (I): From a simple classical model [PDF]
, 2002 This paper, part I of a two-part project, aims at answering the simple question 'what is spontaneous symmetry breaking?' by analyzing from a philosophical perspective a simple classical model.
Liu, Chuang
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Democratic Public Discourse in the Coming Autarchic Communities [PDF]
Meta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2010 The main purpose of this article is to tackle the problem of living together – as dignified human beings – in a certain territory in the field of social philosophy, on the theoretical grounding ensured by some remarkable exponents of the Austrian School −
Gheorghe-Ilie Farte
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Журнал институциональных исследований, 2018 The article presents an analysis of the interaction of social institutions such money and representative democracy in the Grand Principality of Litva.
Aliaksandr Kavaliou
doaj
Advanced Science, 2023 Intrinsic plasticity of neurons, such as spontaneous threshold lowering (STL) to modulate neuronal excitability, is key to spatial attention of biological neural systems.
Yang Jiang +16 more
doaj +1 more source