Early pneumothorax as a feature of response to crizotinib therapy in a patient with ALK rearranged lung adenocarcinoma. [PDF]
Background: Single arm phase 1 and 2 studies on Crizotinib in ALK-positive patients so far have shown rapid and durable responses. Spontaneous pneumothoraces as a result of response to anti-cancer therapy are rare in oncology but have been documented in ...
AT Shaw +18 more
core +1 more source
Exercise‐induced dynamic hyperinflation in chronic obstructive pulmonary disease
Abstract Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease caused by inhalation of noxious particles, most commonly cigarette smoking. The consequent changes in airways, lung parenchyma and pulmonary vasculature lead to increased resistive, elastic and threshold loads and impaired capacity of the respiratory muscle pump. COPD
Rebecca F. D'Cruz +2 more
wiley +1 more source
Spontaneous Lung Herniation Leading to Extensive Subcutaneous Emphysema, Pneumothorax, Pneumomediastinum, and Pneumopericardium. [PDF]
Spontaneous lung herniation is a rare phenomenon in which the lung parenchyma along with the pleural membranes protrudes outside their usual boundaries and can lead to a wide variety of complications.
Ghani, Ali R. +4 more
core +1 more source
Spontaneous Pneumomediastinum and Bilateral Pneumothoraces in a Patient with Bleomycin-Induced Pneumonitis [PDF]
Bleomycin lung toxicity is well established and can manifest as bleomycin-induced pneumonitis, but pneumomediastinum and pneumothorax are very rare complications.
Barras, Matthieu, Uhlmann, Marc
core +3 more sources
Abstract Attenuation of sympathetic vasoconstriction during exercise (functional sympatholysis) contributes to skeletal muscle oxygen delivery–utilization matching. However, the extent to which muscle contractions impact noradrenergic regulation of interstitial oxygen pressures (PO2is${P_{{{\mathrm{O}}_2}}}_{{\mathrm{is}}}$; the driving force for blood–
Edward T. N. Calvo +10 more
wiley +1 more source
Assessment of spontaneous pneumothorax in adults in a tertiary care hospital
Context: Pneumothorax continues to be a major cause of morbidity and mortality among respiratory patients, but there is a paucity of data regarding etiology, clinical profile, management, and outcome of spontaneous pneumothorax (SP), from this part of ...
Aparup Dhua +7 more
doaj +1 more source
ABSTRACT Background and Aims The Endoscopic Pressure Study Integrated System (EPSIS) is a novel endoscopic tool to assess lower esophageal sphincter (LES) function by monitoring intragastric pressure (IGP) through insufflation. While previous studies have confirmed its diagnostic utility for LES dysfunction‐related disorders such as gastroesophageal ...
Miyuki Iwasaki +9 more
wiley +1 more source
Pneumothorax: An update on clinical spectrum, diagnosis and management
Pneumothorax is defined as air in the pleural space and is characterised by chest pain and breathlessness. It is commonly divided into spontaneous and non-spontaneous subtypes based on the underlying mechanism.
Beenish Iqbal +2 more
doaj +1 more source
Incidence of primary spontaneous pneumothorax: a validated, register-based nationwide study
Objectives The incidence of primary spontaneous pneumothorax is partly unknown. Commonly quoted estimates were published decades ago and recent large-scale epidemiological publications lack validation.
Winnie Hedevang Olesen +4 more
doaj +1 more source
Changes in Spinal Neural Circuit Plasticity in a Rat Sciatic Nerve Transection Model
Following sciatic nerve transection (SNT), corticospinal tract (CST) labeling in the lumbar gray matter remained unchanged, whereas motor neurons showed soma atrophy with reduced perisomatic vesicular glutamate transporter 1 (vGlut1) and vesicular acetylcholine transporter (vAchT) inputs.
Katsuyuki Konishi +13 more
wiley +1 more source

