Results 81 to 90 of about 88,616 (305)

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Coordination, Division of Labor, and Open Content Communities: Template Messages in Wiki-Based Collections [PDF]

, 2009
In this paper we investigate how in commons based peer production a large community of contributors coordinates its efforts towards the production of high quality open content. We carry out our empirical analysis at the level of articles and focus on the
Dalle, Jean-Michel, den Besten, Matthijs, Loris, Gaio, Rossi, Alessandro   +3 more
core  

Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Adrian J. Thrasher, Arturo Sala, Chow, Croce, Dale, Daniel A. Morgenstern, Giorgia Santilli, Ikeda, Izabela Piotrowska, John Anderson, Katie Pearson, Marco D'Alicarnasso, Nourredine Himoudi, Olesya Chayka, Sandra Cantilena   +14 more
core   +2 more sources

Bridging home, school and community to address educational inequality: Supporting educational trajectories through community bridge work

British Educational Research Journal, EarlyView.
Abstract This paper explores the role of community stakeholders in supporting the educational trajectories of students experiencing socio‐economic disadvantage in the Irish context. Building on international and national policy debates, the study examines how community‐based organisations, statutory services and outreach initiatives work alongside ...
Aoife Joy Keogh, Deirdre McGillicuddy
wiley   +1 more source

Subterranean environments contribute to three‐quarters of classified ecosystem services

Biological Reviews, EarlyView.
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola, David Brankovits, Tiziana Di Lorenzo, Isabel R. Amorim, Raluca Ioana Bancila, Adrià Bellvert, Enrico Bernard, Anna Blomberg, Paulo A.V. Borges, Martina Cappelletti, Rodrigo Lopes Ferreira, Rosalina Gabriel, Diana M. P. Galassi, Laura Garzoli, Vasilis Gerovasileiou, Grant C. Hose, Kathryn L. Korbel, Simone Martino, Ana Z Miller, Nataša Mori, Veronica Nanni, Giuseppe Nicolosi, Mattia Saccò, Troy S. Sakihara, Marconi Souza Silva, Anne E. Tamalavage, Maja Zagmajster, Efraín Chávez, Christian Griebler, Pedro Cardoso, Alejandro Martínez   +30 more
wiley   +1 more source

Idiopathic Membranous Nephropathy: Glomerular Pathological Pattern Caused by Extrarenal Immunity Activity

Frontiers in Immunology, 2020
Idiopathic membranous nephropathy (IMN) is a pathological pattern of glomerular damage caused by an autoimmune response. Immune complex deposition, thickness of glomerular basement membrane, and changes in the podocyte morphology are responsible for the ...
Wenbin Liu, Chang Gao, Zhiyuan Liu, Haoran Dai, Zhendong Feng, Zhaocheng Dong, Yang Zheng, Yu Gao, Xuefei Tian, Baoli Liu   +9 more
doaj   +1 more source

Cognitive-behavioral therapy for obsessive-compulsive disorder: access to treatment, prediction of long-term outcome with neuroimaging. [PDF]

, 2015
This article reviews issues related to a major challenge to the field for obsessive-compulsive disorder (OCD): improving access to cognitive-behavioral therapy (CBT).
Feusner, Jamie D, O'Neill, Joseph
core   +2 more sources

Taking Fuel From the Fire: Regulating the Introduction of Rape Myth Infused and Irrelevant Evidence About Complainants in Rape Trials

Behavioral Sciences &the Law, EarlyView.
ABSTRACT This article considers how victim‐blaming and stereotypical attitudes about appropriate victim behaviour can impact upon the operation of rape trials, particularly by prejudicing a complainant's testimony where s/he can be portrayed as having departed from the stereotypical norm of a ‘real victim’.
Susan Leahy
wiley   +1 more source

A “Wait-and-See” Approach to Quiescent Single-System Langerhans Cell Histiocytosis to Spare Children From Chemotherapy

Frontiers in Pediatrics, 2020
Background: Langerhans Cell Histiocytosis (LCH) is a childhood disorder of histiocytes that is generally treated with systemic chemotherapy. Spontaneous resolution has been previously reported in Single System LCH (SS-LCH), which is less aggressive than ...
Bernice Oh, Shawn Lee, Yuhe Ke, Miriam Kimpo, Allen Yeoh, Thuan Chong Quah   +5 more
doaj   +1 more source