Results 81 to 90 of about 3,173,146 (256)
Spontaneous Symmetry Breaking in Quantum Systems: Emergence or Reduction? [PDF]
, 2013 Beginning with Anderson (1972), spontaneous symmetry breaking (SSB) in infinite quantum systems is often put forward as an example of (asymptotic) emergence in physics, since in theory no finite system should display it. Even the correspondence between
Landsman, Nicolaas P. +2 more
core +2 more sources
Drug-induced liver injuries in pregnancy in the context of polypragmasy
Безопасность и риск фармакотерапии, 2018 Pregnancy is characterized by overexertion of metabolism in the liver and some changes in metabolism, which can lead to various, including severe organ, damage. During pregnancy, according to international epidemiological studies, more than 80 % of women
N. Yu. Velts +4 more
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
ON THE SAFETY OF ANTIBACTERIAL DRUGS USED IN PEDIATRICS
Безопасность и риск фармакотерапии, 2018 The safety of application of different groups of antibacterial drugs in pediatrics among children is discussed in this article. The analysis was made of spontaneous reports in the national database for 2012, containing information about serious adverse ...
A. R. Titova +6 more
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BMC PsychiatryBackground Psychiatric diseases are often treated with several drugs. In addition, the risk of developing somatic comorbidities which may require drug therapy is higher in patients with than in patients without psychiatric diseases.
Diana Dubrall +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Retrospective Analysis of Spontaneous Reports of Fatal Adverse Reactions Associated with Lidocaine
Безопасность и риск фармакотерапииSCIENTIFIC RELEVANCE. Pain and pain relief are among the most important problems that arise during medical procedures. Lidocaine is used not only as an anaesthetic during interventions but also as a diluent for other medicinal products.
A. V. Matveev +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
The Russian study of «off-label» drug use in pediatric practice: 2015 vs 2012
Качественная клиническая практика, 2018 Purpose. To study and compare the structure of off-label drug use in children in 2012 and 2015 by means of analysis of the national pharmacovigilance database. Materials and methods.
A. R. Titova +3 more
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