Results 51 to 60 of about 14,329 (134)

A Case of Spontaneous Tumor Lysis Syndrome in Malignant Melanoma

World Journal of Oncology, 2016
A 62-year-old man with a complaint of back pain lasting 2 months was admitted. He also presented a huge abdominal tumor. Diagnostic imaging showed metastatic tumors in the liver, lumbar vertebrae and bilateral lung. An ultrasound-guided needle biopsy revealed a lung tumor containing melanic tissue.
Takeuchi, Nobumichi, Miyazawa, Shun, Ohno, Zentaro, Yoshida, Sonomi, Tsukamoto, Tetsu, Fujiwara, Masayuki   +5 more
openaire   +3 more sources

Tumor lysis syndrome developing intraoperatively

Journal of Anaesthesiology Clinical Pharmacology, 2011
Tumor lysis syndrome is a potentially life threatening condition which is most commonly encountered in patients being treated with chemotherapy. We report a case of spontaneous tumor lysis syndrome that developed intraoperatively in a patient with ...
Ankur Verma, Ruchi Mathur, Munish Chauhan, Prashant Ranjan   +3 more
doaj   +1 more source

Spontaneous tumor lysis syndrome in small cell lung cancer [PDF]

Baylor University Medical Center Proceedings, 2017
Tumor lysis syndrome is a set of metabolic disturbances that can be seen during the destruction of tumor cells and is an oncologic and metabolic emergency. The syndrome is rare in those with solid tumors, and even more rare in those with solid tumors who have not yet received chemotherapy.
Ryan K, Dean, Rogin, Subedi, Mijung, Lee
openaire   +4 more sources

Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature

Case Reports in Medicine, 2012
Tumor lysis syndrome (TLS) is an oncologic emergency that is caused by massive tumor cell lysis. It is commonly associated with hematological cancers like leukemia and lymphoma and uncommonly with solid nonhematologic tumors as well. However, spontaneous
Neeraj Saini, Kyeong Pyo Lee, Smita Jha, Sanket Patel, Neelima Bonthu, Ankit Kansagra, Ashmeet Bhatia, Sandra E. Martinez, Jaymin Patel, Sarah Altamimi, Sara Ghotb   +10 more
doaj   +1 more source

An HIV Associated Plasmablastic Lymphoma With Spontaneous Tumor Lysis Syndrome. [PDF]

Cureus, 2020
Plasmablastic lymphoma (PBL) is a rare and aggressive B-cell Non-Hodgkin lymphoma (NHL) associated with immunocompromised states such as HIV. We present a case of PBL in an HIV patient presenting as spontaneous tumor lysis syndrome and discuss the clinical challenges hence encountered.
Al Sbihi AF, Singh P, Manasrah N, Kandah E, Appel J.   +4 more
europepmc   +4 more sources

Spontaneous acute tumor lysis syndrome with advanced gastric cancer [PDF]

Journal of Korean Medical Science, 2001
Acute tumor lysis syndrome (TLS) occurs frequently in hematologic malignancies such as high-grade lymphomas and acute leukemia, which are rapidly proliferating and chemosensitive tumors. It occurs rarely in solid tumors and has never been reported in gastric adenocarcinoma.
I S, Woo, J S, Kim, M J, Park, M S, Lee, R W, Cheon, H M, Chang, J S, Ahn, J A, Lee, Y I, Park, Y S, Park, J W, Shim, I, Yang   +11 more
openaire   +2 more sources

Spontaneous Tumor Lysis Syndrome in Metastatic Melanoma.

World journal of oncology, 2011
Tumor lysis syndrome (TLS) complicating non-hematologic malignancy is infrequent and spontaneous TLS is a very rare occurrence in patients with solid tumors. We report a case of spontaneous TLS in a patient with metastatic melanoma. Clinicians should have awareness of the possibility of spontaneous TLS in patients with solid tumors and should recognize
Song, Mingchen, Chan, Chris C. W., Stoeckel, David A.   +2 more
openaire   +2 more sources

Metastatic adult neuroblastoma with spontaneous tumor lysis syndrome

Autopsy and Case Reports, 2021
Neuroblastoma (NB) is a solid tumor of the sympathetic nervous system, most commonly found in childhood, standing for 7% of all pediatric malignancies. The incidence in adults is markedly smaller: 1 case per 10 million adults per year. We report the case
Tarsila Vieceli, Ana Laura Jardim Tavares, Renata Pibernat de Moraes, Gustavo Adolpho Moreira Faulhaber   +3 more
doaj  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source