Results 121 to 130 of about 343,330 (314)
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
Integral group ring of the McLaughlin simple group
We consider the Zassenhaus conjecture for the normalized unit group of the integral group ring of the McLaughlin sporadic group McL.
Bódi, Viktor +3 more
core
DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout
A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li +12 more
wiley +1 more source
Mining interesting imperfectly sporadic rules
Detecting association rules with low support but high confidence is a difficult data mining problem. To find such rules using approaches like the Apriori algorithm, minimum support must be set very low, which results in a large number of redundant rules. We
Nathan Rountree +5 more
core +1 more source
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao +25 more
wiley +1 more source
Emerging therapeutic options for sporadic inclusion body myositis
Lindsay N Alfano, Linda P Lowes Nationwide Children’s Hospital, Center for Gene Therapy, Columbus, OH, USA Abstract: Sporadic inclusion body myositis is the most common inflammatory muscle disorder preferentially affecting males over the age of ...
Lowes LP, Alfano LN
core
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin +12 more
wiley +1 more source
Formation & Movement of Sporadic E [PDF]
141-144Calculation of the electron density profile is done on the basis of the redistribution theory of sporadic E-Iayer. The downward movement of the sequential sporadic E is discussed with the help of the corkscrew mechanism, and the decreasing ...
Singh, B. +3 more
core
Finding Sporadic Rules Using Apriori-Inverse
We define sporadic rules as those with low support but high confidence: for example, a rare association of two symptoms indicating a rare disease.
Nathan Rountree +3 more
core +1 more source
Oligopeptides/DNA Coacervate Droplets as Macromolecular Delivery Microcarriers
Oligopeptide–DNA coacervates formed via liquid–liquid phase separation serve as programmable carriers for macromolecular cargos, entering cells through lipid raft–associated pathways and subsequently undergoing enzyme triggered intracellular disassembly driven by DNA degradation processes, thereby enabling efficient, controlled, and spatially defined ...
Linyi Zhang +5 more
wiley +1 more source

