Results 81 to 90 of about 343,330 (314)

Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease [PDF]

, 2009
Several molecular subtypes of sporadic Creutzfeldt-Jakob disease have been identified and electroencephalogram and cerebrospinal fluid biomarkers have been reported to support clinical diagnosis but with variable utility according to subtype.
Summers, DM, Collins, S.J. (Steven), Brandel, J.P., Meissner, B, Meissner, B., Cras, P. (Patrick), Varges, D., Jansen, GH, Cras, Patrick, Pimentel, J, Brandel, J P, Smith, P., Taratuto, Ana Lia, van Duijn, Cornelia M., Begue, Christian, Summers, D. M., Summers, D.M., Jansen, G. H., Hewer, Ekkehard, Ladogana, Anna, Jansen, Gerard H, Will, Robert G., Schuur, M. (Maaike), Haik, S., Sanchez-Juan, P. (Pascual), Begue, C, Brandel, JP, Collins, S J, Heinemann, U., Haik, Stephane, Stokin, G B, Zerr, I., Schuur, M, Pimentel, Jose, Breithaupt, M., Taratuto, A, Sanchez-Juan, P, van Duijn, C., Stokin, GB, Breithaupt, Maren, Collins, SJ, Kallenberg, K., Sanchez-Juan, P., Collie, Donald A., Sanchez-Juan, Pascual, Hewer, E, Ladogana, A. (Anna), Schuur, M., Romero, C, Tikka-Kleemola, P. (Päivi), Cras, P., Schuur, Maaike, Romero, Carlos, Ladogana, A, Haik, S, Duijn, Cornelia, Stokin, G. B., Taratuto, A., Collie, D, Stokin, G.B., Brandel, J. P., Romero, C., Smith, P, Jansen, G H, Collie, D., Begue, C., Heinemann, U, Will, R G, Smith, Pete, Pocchiari, M., Collins, S. J., Pocchiari, Mauricio, Ladogana, A., Will, R. G., Will, RG, Meissner, Bettina, Summers, D M, Breithaupt, M, Jansen, G.H. (Gerard), Kallenberg, Kai, Hewer, E., Will, R.G., Cras, P, Zerr, I, Roberts, H., Jansen, Gerard H., Pocchiari, M, van Duijn, C, Pocchiari, M. (Maurizio), Varges, Daniel. A., Roberts, H, Brandel, Jean-Philippe, Kallenberg, K, Varges, D, Pimentel, J.   +94 more
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C-cell hyperplasia in sporadic and familial medullary thyroid carcinoma

Indian Journal of Pathology and Microbiology, 2018
Context: C-cell hyperplasia (CCH) is characterized by increased mass of C-cells and has been identified as a precursor condition for medullary thyroid carcinoma (MTC). Varying proportion of MTCs is associated with CCH in different studies.
Mahima Yadav, Vinita Agrawal, Krushna Chandra Pani, Ritu Verma, Sushila Jaiswal, Anjali Mishra, Rakesh Pandey   +6 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Efficient transmission and characterization of creutzfeldt-jakob disease strains in bank voles.

, 2006
Transmission of prions between species is limited by the "species barrier," which hampers a full characterization of human prion strains in the mouse model.
Bari Michele A. Di, Boyle, Aileen, Lipp Hans-Peter, Gabriele Vaccari, Maurizio Pocchiari, Cardone Franco, Sbriccoli Marco, Claudia Cartoni, Sbriccoli, Marco, Boyle Aileen, Dell'Omo, Giacomo, Nonno, Romolo, Di Bari, Michele A, Nonno Romolo, Franco Cardone, Galeno, Roberta, Marco Sbriccoli, Paola Fazzi, Vaccari Gabriele, Cartoni, Claudia, Cardone, Franco, Galeno Roberta, Loredana Ingrosso, Roberta Galeno, Fazzi, Paola, Lipp, Hans-Peter, Fazzi Paola, Michele A Di Bari, Ingrosso Loredana, Hans-Peter Lipp, Ingrosso, Loredana, Pocchiari, Maurizio, Umberto Agrimi, Pocchiari Maurizio, Vaccari, Gabriele, Agrimi, Umberto, Giacomo Dell'Omo, Moira Bruce, Aileen Boyle, Dell'Omo Giacomo, Agrimi Umberto, Bruce Moira, Bruce, Moira, Romolo Nonno, Cartoni Claudia   +44 more
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Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Base sizes for sporadic simple groups

, 2010
Let G be a permutation group acting on a set . A subset of is a base for G ifits pointwise stabilizer in G is trivial. We write b(G) for the minimal size of a base forG.
Robert A. Wilson, O'Brien, E.A., Wilson, Robert, Timothy C. Burness, E. A. O’Brien, Wilson, Robert A., O'Brien, Eamonn, Burness, Tim C, Burness, Timothy C.   +8 more
core   +1 more source

Analysis of the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in a general hospital

Бюллетень сибирской медицины
Aim. To analyze the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in 2017–2023 in a multidisciplinary inpatient facility.Materials and methods.
M. V. Zavyalova, A. V. Zavyalov, D. S. Pismenny, L. V. Pikalova, L. D. Zhuykova, Yu. M. Zhuykova, M. Yu. Grishchenko, S. V. Vtorushin, N. V. Litvyakov, M. V. Perelmuter   +9 more
doaj   +1 more source

A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley   +1 more source

DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy [PDF]

, 2014
Colorectal cancers (CRC) are thought to have genetic instability in the form of either microsatellite instability (MSI) or chromosomal instability (CIN).
Ilyas, Mohammad, Lane, Nina, Robins, A, Zaitoun, Abed M., Kindle, Karin, Fadhil, W, Zaitoun, A, Ilyas, M, Kindle, K, Lane, N, Robins, Adrian, Jackson, D, Jackson, Darryl, Fadhil, Wakkas   +13 more
core   +1 more source