Results 21 to 30 of about 3,366 (193)

Amlodipine and lufenuron as repurposing drugs against Sporothrix brasiliensis. [PDF]

PeerJ, 2023
Background Sporotrichosis caused by Sporothrix brasiliensis is a globally emerging infectious disease with limited therapeutic options. Thus, we aimed to evaluate the in vitro activity of amlodipine (AML) and lufenuron (LUF) alone and their interaction with itraconazole (ITZ), the first-choice drug against S. brasiliensis.
Poester VR, Hidalgo JED, Jardim LS, Trápaga MR, Rabello VBS, Almeida-Paes R, Zancope-Oliveira RM, Xavier MO.   +7 more
europepmc   +4 more sources

Tattooing as a gateway to Sporothrix brasiliensis infection. [PDF]

Med Mycol Case Rep, 2022
Recently, sporotrichosis caused by Sporothrix brasiliensis transmitted during tattooing process was described in the epicenter of the Brazilian epidemic sporotrichosis. We report a similar case of this mycosis in a patient recently tattooed, but probably infected by a sick cat instead of via a contaminated procedure.
Poester VR, Severo CB, da Silva CAE, Stevens DA, Trápaga MR, Xavier MO.   +5 more
europepmc   +4 more sources

New Insights on Transmission of Sporothrix brasiliensis. [PDF]

Mycoses
ABSTRACTBackgroundSporotrichosis is the most prevalent saprozoonotic implantation mycosis worldwide.ObjectivesA prospective experimental study was performed to evaluate persistence on surfaces such as stainless steel medium‐density fiberboard (MDF) wood, tile, and polyester fabric.MethodsThe different surfaces were homogeneously contaminated using the ...
Cognialli RCR, Queiroz-Telles F, Cavanaugh AM, Rediguieri BC, Santos GCD, Matias FM, Filho LM, Neto ENM, Surek M, Vicente VA, Santos-Weiss ICR.   +10 more
europepmc   +3 more sources

Rising Incidence of Sporothrix brasiliensis Infections, Curitiba, Brazil, 2011-2022. [PDF]

Emerg Infect Dis, 2023
Les épidémies zoonotiques de sporotrichose sont en augmentation au Brésil. Nous avons examiné et décrit l'émergence de la sporotrichose transmise par le chat (STC) causée par le pathogène fongique Sporothrix brasiliensis. Nous avons calculé l'incidence et cartographié la distribution géographique des cas à Curitiba, au Brésil, en examinant les dossiers
Cognialli RCR, Cáceres DH, Bastos FAGD, Cavassin FB, Lustosa BPR, Vicente VA, Breda GL, Santos-Weiss I, Queiroz-Telles F.   +8 more
europepmc   +5 more sources

Differential Recognition of Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa by Human Monocyte-Derived Macrophages and Dendritic Cells

Infection and Drug Resistance, 2023
Manuela Gómez-Gaviria,1 Iván Martínez-Duncker,2 Laura C García-Carnero,1 Héctor M Mora-Montes1 1Departamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Guanajuato, Guanajuato México; 2Laboratorio ...
Gómez-Gaviria M, Martínez-Duncker I, García-Carnero LC, Mora-Montes HM   +3 more
doaj   +1 more source

Treatment of Human Sporotrichosis Caused by Sporothrix brasiliensis. [PDF]

J Fungi (Basel), 2022
We describe the successful treatment of a series of 30 zoonotic sporotrichosis cases from southern Brazil. Sporothrix brasiliensis was the species genotypically identified in all 25 confirmed cases. Five other cases were classified as probable, without laboratory confirmation, but with clinical and epidemiological data of cat-transmitted sporotrichosis.
Poester VR, Basso RP, Stevens DA, Munhoz LS, de Souza Rabello VB, Almeida-Paes R, Zancopé-Oliveira RM, Zanchi M, Benelli JL, Xavier MO.   +9 more
europepmc   +5 more sources

Differential Recognition of Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa by Human Monocyte-Derived Macrophages and Dendritic Cells. [PDF]

Infect Drug Resist, 2023
Sporotrichosis is a mycosis frequently caused by Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa. The cell wall is a species-specific fungal structure with a direct role in activating the host's immune response. The current knowledge about anti-Sporothrix immunity comes from studies using S. schenckii or S. brasiliensis and murine
Gómez-Gaviria M, Martínez-Duncker I, García-Carnero LC, Mora-Montes HM.   +3 more
europepmc   +4 more sources

Sporotrichosis Caused by Non-Wild Type Sporothrix brasiliensis Strains. [PDF]

Front Cell Infect Microbiol, 2022
The zoonotic transmission of sporotrichosis due to Sporothrix brasiliensis occurs largely in Rio de Janeiro state, Brazil since the 1990´s. Most patients infected with S. brasiliensis respond well to itraconazole or terbinafine. However, a few patients have a slow response or do not respond to the treatment and develop a chronic infection.
Bernardes-Engemann AR, Tomki GF, Rabello VBS, Almeida-Silva F, Freitas DFS, Gutierrez-Galhardo MC, Almeida-Paes R, Zancopé-Oliveira RM.   +7 more
europepmc   +4 more sources

First Cases of Feline Sporotrichosis Caused by Sporothrix brasiliensis in Paraguay. [PDF]

J Fungi (Basel), 2023
Sporothrix brasiliensis is an emerging fungal pathogen causing cat-transmitted sporotrichosis, an epi-zoonosis affecting humans, cats and dogs in Brazil and now spreading to neighboring South American countries. Here, we report the first two autochthonous cases of cat-transmitted sporotrichosis in Paraguay.
do Prado CM, Razzolini E, Santacruz G, Ojeda L, Geraldo MR, Segovia N, Pereira Brunelli J, Vicente VA, Svoboda WK, Queiroz-Telles F.   +9 more
europepmc   +4 more sources

Beyond Domestic Cats: Environmental Detection of Sporothrix brasiliensis DNA in a Hyperendemic Area of Sporotrichosis in Rio de Janeiro State, Brazil

Journal of Fungi, 2022
In Brazil, sporotrichosis has transitioned from a rural to urban disease, driven by a shift in the initiation of infection from the accidental inoculation of organic matter to the traumatic implantation of the fungus by cats.
Fernando Almeida-Silva, Vanessa Brito de Souza Rabello, Bruno de Souza Scramignon-Costa, Rosely Maria Zancopé-Oliveira, Priscila Marques de Macedo, Rodrigo Almeida-Paes   +5 more
doaj   +1 more source