Structural diversity and biological significance of glycosphingolipids in pathogenic and opportunistic fungi [PDF]
Glycosphingolipids (GSLs) are ubiquitous membrane components and have key roles in biological systems, acting as second messengers or modulators of signal transduction by affecting several events, ranging from cell adhesion, cell growth, cell motility ...
Anita Hilda Straus +5 more
core +2 more sources
Cat-transmitted sporotrichosis caused by Sporothrix brasiliensis has become a major public health concern and presents a distinct divergence from the traditional epidemiology of sporotrichosis.
John A. Rossow +7 more
doaj +1 more source
Resistance of melanized yeast cells of Paracoccidioides brasiliensis to antimicrobial oxidants and inhibition of phagocytosis using carbohydrates and monoclonal antibody to CD18 [PDF]
Paracoccidioides brasiliensis, a thermal dimorphic fungal pathogen, produces a melanin-like pigment in vitro and in vivo. We investigated the involvement of carbohydrates and monoclonal antibody to CD18, on phagocytosis inhibition, involving macrophage ...
Casadevall, Arturo +7 more
core +3 more sources
Polyketides, Toxins and Pigments in Penicillium marneffei [PDF]
Penicillium marneffei (synonym: Talaromyces marneffei) is the most important pathogenic thermally dimorphic fungus in China and Southeastern Asia. The HIV/AIDS pandemic, particularly in China and other Southeast Asian countries, has led to the emergence ...
Lau, SKP, Tam, EWT, Tsang, CC, Woo, PCY
core +2 more sources
Terbinafine is a recommended therapeutic alternative for patients with sporotrichosis who cannot use itraconazole due to drug interactions or side effects. Melanins are involved in resistance to antifungal drugs and Sporothrix species produce three different types of melanin.
Rodrigo Almeida-Paes +5 more
openaire +4 more sources
Genome size and ploidy of Paracoccidioides brasiliensis reveals a haploid DNA content: Flow cytometry and GP43 sequence analysis [PDF]
The aim of this study was to evaluate genome size and ploidy of the dimorphic pathogenic fungus Paracoccidioides brasiliensis. The cell cycle analysis of 10 P. brasiliensis isolates by flow cytometry (FCM) revealed a genome size ranging from 26.3+/-0.1Mb
Almeida, A. J. +9 more
core +1 more source
Comparison of the human immune responses to recombinant proteins representing three distinct surface proteins of Plasmodium vivax merozoites [PDF]
Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Departamento de Microbiologia, Imunologia e ParasitologiaUniversidade Federal do Pará Departamento de PatologiaCenters for Disease Control and Prevention Division of Parasitic
Barnwell, John W. +7 more
core +3 more sources
INTRODUCTION: We compared indicators of oxidative stress in the tissue of mice infected with strains from Sporothrix schenckii complex. METHODS: Mice were inoculated with Sporothrix brasiliensis, Sporothrix schenckii sensu stricto, Sporothrix globosa,
Débora Nunes Mario +6 more
doaj +1 more source
Proteomics-Based Characterization of the Humoral Immune Response in Sporotrichosis: Toward Discovery of Potential Diagnostic and Vaccine Antigens. [PDF]
BACKGROUND:Sporothrix schenckii and associated species are agents of human and animal sporotrichosis that cause large sapronoses and zoonoses worldwide.
Anderson Messias Rodrigues +9 more
doaj +1 more source
Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus [PDF]
Universidade Federal de São Paulo (UNIFESP) Department of PhysiologyUNIFESP, Department of ...
Covolan, Luciene +3 more
core +2 more sources

