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Phenotypic and genotypic characterization of Colombian clinical isolates of Sporothrix spp. [PDF]

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2023
Introduction. For over a century, Sporothrix schenckii was considered the sole species responsible for sporotrichosis. In 2007, scientific community confirmed the disease could be caused by various Sporothrix species.
Laura C. Álvarez-Acevedo   +10 more
doaj   +4 more sources

Ploidy Determination in the Pathogenic Fungus Sporothrix spp. [PDF]

open access: yesFrontiers in Microbiology, 2019
The pathogenic clade of the Sporothrix genus comprises the etiological agents of sporotrichosis, a worldwide emergent disease. Despite the growing understanding of their successful pathogen traits, there is little information on genome sizes and ploidy ...
Beatriz H. Ferreira   +18 more
doaj   +6 more sources

Cell walls of the dimorphic fungal pathogens Sporothrix schenckii and Sporothrix brasiliensis exhibit bilaminate structures and sloughing of extensive and intact layers [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
Sporotrichosis is a subcutaneous mycosis caused by pathogenic species of the Sporothrix genus. A new emerging species, Sporothrix brasiliensis, is related to cat-transmitted sporotrichosis and has severe clinical manifestations.
Leila Maria Lopes Bezerra   +2 more
exaly   +11 more sources

Selective depletion of regulatory T cells enhances the immunogenicity of a recombinant-based vaccine against Sporothrix spp [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionRegulatory T cells (Tregs) have been shown to limit the protective immune response against pathogenic species of the fungus Sporothrix spp, the causal agent of sporotrichosis. However, the specific function of Tregs during vaccination against
Alexander Batista-Duharte   +3 more
doaj   +4 more sources

Analyses of the Genetic Diversity and Population Structures of Sporothrix spp. Clinical Isolates from Paraíba, Brazil [PDF]

open access: yesJournal of Fungi
Sporotrichosis is a subcutaneous mycosis of global distribution, capable of affecting both humans and animals, and caused by species of the genus Sporothrix spp.
Larissa Alves da Silva   +9 more
doaj   +4 more sources

Photodynamic inactivation strategies for maximizing antifungal effect against Sporothrix spp. and Candida albicans in an in vitro investigation. [PDF]

open access: yesPLoS Neglected Tropical Diseases
BackgroundSporotrichosis is a zoonotic disease caused by the dimorphic fungus Sporothrix spp., leading to skin lesions that can, in some cases, progress and result in the death of infected individuals.
Amanda Regina Rocha   +4 more
doaj   +5 more sources

Sporothrix spp. Biofilms Impact in the Zoonotic Transmission Route: Feline Claws Associated Biofilms, Itraconazole Tolerance, and Potential Repurposing for Miltefosine [PDF]

open access: yesPathogens, 2022
Sporotrichosis is the most prevalent subcutaneous mycosis globally, and it is typically caused by direct inoculation of the soil saprophytic fungus Sporothrix spp. into the patients’ skin.
Giulia Maria Pires dos Santos   +6 more
doaj   +2 more sources

Multicenter, International Study of MIC/MEC Distributions for Definition of Epidemiological Cutoff Values for Sporothrix Species Identified by Molecular Methods [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2017
Clinical and Laboratory Standards Institute (CLSI) conditions for testing the susceptibilities of pathogenic Sporothrix species to antifungal agents are based on a collaborative study that evaluated five clinically relevant isolates of Sporothrix ...
Rodrigo Almeida-Paes   +2 more
exaly   +3 more sources

In Vitro Evidence for the Efficacy of Manuka Honey and Its Components Against the Major Human Pathogenic Sporothrix Species [PDF]

open access: yesPharmaceuticals
Background/Objectives: While various clinical manifestations occur in sporotrichosis, cutaneous forms predominate. The recommended sporotrichosis treatment is itraconazole, an antifungal with certain restrictions.
Andrea Reis Bernardes-Engemann   +9 more
doaj   +2 more sources

Exploring virulence and immunogenicity in the emerging pathogen Sporothrix brasiliensis [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2017
Sporotrichosis is a polymorphic chronic infection of humans and animals classically acquired after traumatic inoculation with soil and plant material contaminated with Sporothrix spp. propagules.
Paula Portella Della Terra   +2 more
exaly   +2 more sources

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