Results 181 to 190 of about 2,364,150 (385)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Body Talk: Male Athletes Reflect on Sport, Injury, and Pain [PDF]

open access: yes, 1994
This paper examines how participation in physically demanding sport, with its potential and actual injurious outcomes, both challenges and reinforces dominant notions of masculinity. Data from 16 in-depth interviews with former and current Canadian adult
McTeer, William   +2 more
core   +1 more source

The Sport Concussion Assessment Tool 5th Edition (SCAT5): Background and rationale

open access: yesBritish Journal of Sports Medicine, 2017
R. Echemendia   +25 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Recovery and Performance in Sport: Consensus Statement.

open access: yesInternational Journal of Sports Physiology and Performance, 2018
M. Kellmann   +20 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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