Results 251 to 260 of about 2,364,150 (385)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A 25-Year Analysis of Athlete Mortality in the United States: Causes, Trends, and the Role of Resource Disparities. [PDF]

Sports Health
Dayal D, Harrell M, Rahaman C, Berta C, Manush A, Casp A, Momaya A.   +6 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Racket Sports-Related Injuries in Youth Athletes: A Narrative Review. [PDF]

Int J Environ Res Public Health
Shrestha M, Usmani A, Karlov S, Harris A, Patel DR.   +4 more
europepmc   +1 more source

Flexibility in Wrestlers, Taekwondoists, and Non-Athletes During the Developmental Ages: The Effects of Sport, Age, and Sex [PDF]

Vassilis Gerodimos, Nikolaos Tsiakaras, Konstantina Karatrantou   +2 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Development of a novel cognitive-motor integration balance assessment in healthy young adults: a pilot study. [PDF]

Front Integr Neurosci
Weinberg SE, Smeha N, Sergio LE, Cleworth TW.   +3 more
europepmc   +1 more source

Curriculum for excellence and the transition to Abertay attributes:the contribution of sport

, 2016
Lowe, Ian
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The Effect of Educational Intervention on Legal Anti-Doping Knowledge and Doping Tendency in Elite Athletes. [PDF]

Sports (Basel)
Sinkovic A, Pivalica D, Jukic I, Pehar M, Pivalica B, Cerkez Zovko I, Sekulic D.   +6 more
europepmc   +1 more source