Results 61 to 70 of about 1,115,331 (279)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Sports Competition Among the Jewish Population in Łódź in the Years 1945–1949

Sport i Turystyka
The liberation of Łódź from German occupation enabled a revival of the Jewish culture, including physical culture. In the years between 1945 and 1949, Jewish people living in the city of Łódź reactivated their sporting movement.
Julian Jaroszewski
doaj   +1 more source

Influences of club connectedness among young adults in Western Australian community-based sports clubs

BMC Public Health, 2020
Background Along with physical benefits, community-based sport provides opportunities to enhance connectedness, an important protective factor of social and emotional health.
Sharyn Burns, Melissa Evans, Jonine Jancey, Linda Portsmouth, Bruce Maycock   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Involvement in sports clubs and informal sport activities of primary and secondary school children in Liechtenstein [PDF]

Revija za Elementarno Izobraževanje, 2016
Sport involvement among children and adolescents has been a central field of research in sport science since years. This paper documents the participation of 11- to 15-year-olds in sport clubs and informal sport activities in Liechtenstein and examines ...
Jürgen Kühnis , Beat Wachter, Christian Frommelt   +2 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Sport clubs in Brazil: facilities, equipment and content in

E-balonmano.com: Revista de Ciencias del Deporte, 2017
Sport is an important phenomenon on XXI Century, and sport clubs are a relevant environment for youth sport. Aim: analyze facilities, equipment and contents in social-clubs in Cáceres City (Mato Grosso State, Brazil).
Jessica Cristiani, João Carlos Bressan, Benjamín Longarela Pérez, Larissa Rafaela Galatti, Riller Silva Reverdito   +4 more
doaj   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Physical activity, sport and health in the City of Brimbank [PDF]

, 2015
Provides a summary of key indicators of participation in physical activity and sport, together with potentially related key demographic characteristics and indicators of health and education, for the City of Brimbank in Melbourne.
Sport and Recreation Spatial
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