Results 61 to 70 of about 7,369,847 (322)

Sport d'élite Suisse: Etat des lieux SPLISS-CH 2019 [PDF]

open access: yes, 2021
L’évolution que connaissent les Jeux Olympiques a aussi une influence sur le sport en Suisse. Le nombre croissant d’épreuves et donc de médailles, et la concurrence internationale qui ne cesse de s’intensifier en font un défi toujours plus grand à ...
Mrkonjic, Michael   +7 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Examining the Outcomes of Sport Specialization for Individual Athletes and the Industry

open access: yesSpectrum, 2020
Sport specialization for young athletes has become a prerequisite for sport achievement, but academics have yet to explore the effects that sport specialization has on athletes’ participation patterns.
Carolina Alongi   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Effects of sport celebrity transgressions in the sport industry [PDF]

open access: yes, 2015
The importance of the brand image of sport celebrities is a growing research topic in marketing communication and sponsorship programmes. However, there is a dearth of research focus on the impact of different types of sport celebrity transgressions on ...
Sassenberg, Anne-Marie
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Physical activity, sport and health in the City of Brimbank [PDF]

open access: yes, 2015
Provides a summary of key indicators of participation in physical activity and sport, together with potentially related key demographic characteristics and indicators of health and education, for the City of Brimbank in Melbourne.
Sport and Recreation Spatial
core  

Reconsidering feminisms and the work of Norbert Elias for understanding gender, sport and sport-related activities [PDF]

open access: yes, 2008
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2008 North West Counties Physical Education Association and SAGE Publications.This paper reconsiders the relationships between feminist ...
Mansfield, L, Mansfield, L.
core   +1 more source

High-performance athletes’ transition out of sport: developing corporate social responsibility [PDF]

open access: yes, 2023
This study investigates high-performance athletes’ experiences of transitioning out of sport and the support provided to them and describes how the findings suggest Corporate Social Responsibility (CSR) initiatives which may inform the development of ...
Hong, Hee Jung, Fraser, Ian
core   +1 more source

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