Sport d'élite Suisse: Etat des lieux SPLISS-CH 2019 [PDF]
L’évolution que connaissent les Jeux Olympiques a aussi une influence sur le sport en Suisse. Le nombre croissant d’épreuves et donc de médailles, et la concurrence internationale qui ne cesse de s’intensifier en font un défi toujours plus grand à ...
Mrkonjic, Michael +7 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Examining the Outcomes of Sport Specialization for Individual Athletes and the Industry
Sport specialization for young athletes has become a prerequisite for sport achievement, but academics have yet to explore the effects that sport specialization has on athletes’ participation patterns.
Carolina Alongi +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Effects of sport celebrity transgressions in the sport industry [PDF]
The importance of the brand image of sport celebrities is a growing research topic in marketing communication and sponsorship programmes. However, there is a dearth of research focus on the impact of different types of sport celebrity transgressions on ...
Sassenberg, Anne-Marie
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Physical activity, sport and health in the City of Brimbank [PDF]
Provides a summary of key indicators of participation in physical activity and sport, together with potentially related key demographic characteristics and indicators of health and education, for the City of Brimbank in Melbourne.
Sport and Recreation Spatial
core
Reconsidering feminisms and the work of Norbert Elias for understanding gender, sport and sport-related activities [PDF]
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2008 North West Counties Physical Education Association and SAGE Publications.This paper reconsiders the relationships between feminist ...
Mansfield, L, Mansfield, L.
core +1 more source
High-performance athletes’ transition out of sport: developing corporate social responsibility [PDF]
This study investigates high-performance athletes’ experiences of transitioning out of sport and the support provided to them and describes how the findings suggest Corporate Social Responsibility (CSR) initiatives which may inform the development of ...
Hong, Hee Jung, Fraser, Ian
core +1 more source

