Results 121 to 130 of about 875,791 (343)
Advanced Science, EarlyView.In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong +11 more
wiley +1 more source
Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics
Advanced Science, EarlyView.This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu +6 more
wiley +1 more source
Sport/performance psychology services to youth elite athletes: challenges and lessons learnt [PDF]
, 2010 Sanjana Kiran
openalex +1 more source
Advanced Science, EarlyView.This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai +12 more
wiley +1 more source
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
"Parenting in Sports" in the Academic Literature: A Bibliometric and Visual Network Analysis
Sportif Bakış Spor ve Eğitim Bilimleri DergisiThis study aims to map the development of the concept of parenting in sport over time and the network of studies related to this concept. In order to identify study trends and gaps in the field of parenting in sport, bibliometric data of open access ...
Emre Bülent ÖĞRAŞ +1 more
doaj +1 more source
Advanced Science, EarlyView.NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou +9 more
wiley +1 more source
"Actually I Was the Star": Managing Attributions in Conversation
Forum: Qualitative Social Research, 2003 In this paper, we outline the parameters of a discursive approach to attributions in sport psychology. Attribution theory has had a strong presence within sport and exercise psychology.
Sara-Jane Finlay, Guy Faulkner
doaj