Results 81 to 90 of about 2,529,711 (362)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Rethinking sport, empire, and American exceptionalism [PDF]
, 2007 This article examines the correlation between sports history and American imperialism and exceptionalism. More specifically, the author argues against a view of sport historiography which excludes debates within social and cultural history.
Pope, Steven W.
core +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Arthroscopic Anatomic Glenoid Reconstruction Without Subscapularis Split
Arthroscopy Techniques, 2015 The role of bone loss from the anterior glenoid in recurrent shoulder instability has been well established. We present a completely arthroscopic technique for reconstructing the anterior glenoid with distal tibial allograft and without a subscapularis ...
Ivan H. Wong, M.D., M.Sc., F.R.C.S.C., Dip. Sports Medicine +1 more
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FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Conceptualizing the adventure-sports coach [PDF]
, 2011 As a comparatively recent development, the adventure-sports coach struggles for a clear and distinct identity. The generic term ‘instructor’ no longer characterizes the role and function of this subgroup of outdoor professionals.
Atherton J. M. +35 more
core +1 more source
MULTISECTORAL MODELS FOR ADVANCED KNOWLEDGE IN CULTURE AND SPORTS ORGANIZATIONAL ENTITIES, IN SMALL AND MEDIUM COMPANIES [PDF]
Strategii Manageriale, 2015 The article used to identify functional and operational links, and determining the quasi-unlimited ecoknowledge in organizational culture and sports entities, in small and medium firms. It is shown that, in fact, increased in absolute economic indicators
Mihai-Daian, CEAUSU
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The highlands of central India; notes on their forests and wild tribes, natural history and sports [PDF]
, 1871 J. Forsyth
openalex +1 more source
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Arthroscopic Stabilization for Chronic Latent Syndesmotic Instability
Arthroscopy Techniques, 2016 Subtle syndesmotic instability not evident on radiography can result in chronic ankle pain. The diagnosis is uncommon, and arthroscopic evaluation remains the gold standard for diagnosis.
CPTM.D. Zackary A. Johnson, M.D., M.Sc., F.R.C.S.C., Dip. Sports Medicine +2 more
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