Results 131 to 140 of about 642,203 (347)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Outcome uncertainty and the couch potato audience [PDF]

open access: yes
Previous studies of attendance demand for professional team sports have failed to yield clear- cut findings on the importance of outcome uncertainty to consumers.
B Buraimo, D Forrest, R Simmons
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The Coaching Workforce Survey 2010 - Baseline Report [PDF]

open access: yes
This report provides information for Sport Northern Ireland on the characteristics of sports coaching in Northern Ireland and the issues and opportunities that coaches face. A sample of sports coaches responded to an online questionnaire promoted through
Barrett, David, Moore, Richard
core  

Markkinointisuunnitelma KooKoo-65 [PDF]

open access: yes, 2015
Opinnäytetyön tarkoituksena oli tehdä markkinointisuunnitelma urheiluseura KooKoo-65:lle. Seuralle ei ole aikaisemmin tehty minkäänlaista suunnitelmaa markkinoinnin avuksi.
Kettunen, Joni
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Competitive Balance and Revenue Sharing in Sports Leagues with Utility-Maximizing Teams [PDF]

open access: yes
This paper develops a contest model of a professional sports league in which clubs maximize a weighted sum of profits and wins (utility maximization).
Helmut Dietl   +2 more
core  

Analisis Pengaruh Kepuasan Pelanggan Atas Customer Relationship Management Terhadap Loyalitas Pelanggan Di Atlas Sports Club Surabaya [PDF]

open access: yes, 2016
Kepuasan pelanggan adalah tingkat perasaan pelanggan setelah membandingkan antara kinerja atau hasil yang dirasakan dengan harapannya. Customer Relationship Management (CRM) adalah proses membangun dan menjaga hubungan dengan pelanggan yang menguntungkan
Andreani, F. (Fransisca)   +2 more
core  

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