Results 61 to 70 of about 1,173,222 (289)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Kaunas city sports club competition assessment of consumer perspective. [PDF]

open access: yes, 2013
Study conducted results showed that the Kaunas city sports The object of the paper: factors influencing the competitiveness of sports clubs. The problem of the research: what factors influence the Kaunas city sports clubs competitiveness.
Polikevičius, Algirdas,
core   +1 more source

Are primary school children attending full-day school still engaged in sports clubs?

open access: yesPLoS ONE, 2019
PurposeSchools and organized sports both offer great chances to promote physical activity among children. Full-day schools particularly allow for extensive participation in extra-curricular physical activities.
Sarah Spengler   +3 more
doaj   +1 more source

The association between physical activity and symptoms of depression in different contexts – a cross-sectional study of Norwegian adolescents

open access: yesBMC Public Health, 2018
Background The purpose was to analyse the association between physical activity taking place in different contexts (sports club, gym, exercise independently and other organized physical activities) and symptoms of depression.
Annette Løvheim Kleppang   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Time-use and environmental determinants of dropout from organized youth football and tennis

open access: yesBMC Public Health, 2018
Background Many adolescents drop out of organized sports. Lack of motivation and competing priorities are known as important reasons for dropout. However, time use factors as well as environmental determinants have been largely neglected in the current ...
Ineke Deelen   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Cornelius Recreation Club Minutes and Constitution, 1947 [PDF]

open access: yes, 1947
The minutes for the Cornelius Recreation Club, describing the events and fundraisers they engaged in during their first year of operation, 1947. The club's constitution and a list of about 60 members is also included.
Cornelius Recreation Club
core   +1 more source

Strategic management of University sports club of MUAF in Brno

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
Paper deals with questions of management of university sports clubs in the Czech Republic. We may summarize the strategic management of University sports clubs into several points in which the club management should clearly answer the following key ...
Dagmar Kudová
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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