Results 131 to 140 of about 48,840 (307)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Sports Business and Multisided Markets: Towards a New Analytical Framework? (Long Version)

open access: yes
Despite still being younger than a decade, the theory of multisided markets has offered numerous valuable insights for the analysis of industries in which a supplier serves two distinct customer groups that are indirectly interrelated through ...
Janina Satzer, Oliver Budzinski
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Beating the Spread: Oregon's Role in the Professional and Amateur Sports Protection Act

open access: yes, 2012
Established in 1859, Oregon, like so many other states, discovered quickly that a strong, viable economy was necessary in order to support the government and the civilians of the state.
Hackel, Derrick K.
core  

Circular-ready and biobased materials for the sports industry

open access: yes
In product development as it is practiced today, the material of each individual component is selected based on its individual suitability for the task in the product. As a result, the composition of sports equipment follows a multi-material design. For
Krüger, Anna
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Sports industry research North America: USA & Canada [PDF]

open access: yes, 2019
The Sports Industry is a potential business that not only involves the game at the field. It includes different aspects like food & beverage, apparel, sponsorship, licensing, events, tourism, and infrastructure (ATKearney, 2011).
Wölfel, Kim   +2 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Management aspects of sports services in Kaunas city : athletics case.

open access: yes, 2014
The object of research: sports services. Problem. The growing competitiveness in sports services industry is important to identify the factors that determine sport services for use, evaluate the athletics of choice and the reasons for the current ...
Stanys, Raivydas,
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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