Results 51 to 60 of about 35,233 (258)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The Position of Sport Industry Science within Sport Science

Journal of Japan Society of Sports Industry, 1994
The "Japan Society of Sports Industry" was founded in order to develop the " Marriage" of sport and industry also by the help of science. Since according to a pragmatic point of view science can be linked to every aspect of reality it is consequent to speak of sport industry science.
openaire   +4 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Athletes’ performance and injury management in sports training using association rules and data mining techniques

Scientific Reports
Optimizing athletic performance while minimizing injury risk remains a central challenge in sports science. Although large volumes of athlete monitoring data are now available, existing studies primarily rely on modeling or isolated statistical analyses,
Lvbo Chen, Bin Mo, XiaoYan Yu
doaj   +1 more source

Research on the Application and Innovation of Digital Technology in the Sports Industry [PDF]

SHS Web of Conferences
With the profound development of digital technology, the digital transformation of the global sports industry has received increasing attention. This paper primarily conducts a comparative analysis of the application characteristics, innovative practices,
Luo Tianzhuo
doaj   +1 more source

Design and Implementation of Sports Industry Information Service Management System Based on Data Mining

Advances in Multimedia, 2022
With the continuous development of sports in China, the tentacles of the sports industry have extended to all walks of life in China. At the same time, with the development of information and network, the information exchange between enterprises and ...
Hang Zhang
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Links between Korean baby boomers’ physical activity and health outcomes: a community health survey study

BMC Public Health
Background This study aimed to explore the association between physical activity (PA) levels and major health issues (obesity, hypertension, and diabetes mellitus) and mental health factors (depression, stress, suicidal thoughts, and cognitive impairment)
Jong-Hyeon Lee, Yong-Jin Yoon
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source