Results 31 to 40 of about 96,837 (266)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Spontaneous Healing of Meniscal Tears With ACL Injuries and Its Impact on Timing of ACL Surgery

Orthopaedic Journal of Sports Medicine
Background: Acute anterior cruciate ligament (ACL) tears with meniscal injuries elevate posttraumatic osteoarthritis risk. While early ACL reconstruction (ACLR) remains prevalent, emerging evidence suggests that delayed intervention may enhance meniscal ...
Chong Zhang, Yourong Chen, Richard Ma MD, Hongjie Huang MD, Jin Cheng, Meng Yang, Xing Xie MD, Jianquan Wang MD   +7 more
doaj   +1 more source

Sports injuries of the wrist [PDF]

Current Reviews in Musculoskeletal Medicine, 2012
Sports injuries involving the hand and wrist are common and, as a result, many different practitioners (athletic trainers, physical therapists, primary care physicians, general orthopedic surgeons) will encounter these injuries. In addition to thorough evaluation, an understanding of typical pathologies seen in the athlete enhances diagnosis and ...
Duretti T, Fufa, Charles A, Goldfarb
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Effect of combining eight weeks of neuromuscular training with dual cognitive tasks on landing mechanics in futsal players with knee ligament dominance defect: a randomized controlled trial

BMC Sports Science, Medicine and Rehabilitation, 2022
Background The performing of jump and landing in futsal simultaneous with divided attention is one of the most common mechanisms of non-contact anterior cruciate ligament (ACL) injury. Neuromuscular training has effectively reduced the risk of ACL injury,
Majid Hamoongard, Malihe Hadadnezhad, Ali Abbasi   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Ultrasound had high accuracy in measuring hip joint capsule thickness

BMC Musculoskeletal Disorders
Background The hip joint capsule is an essential component of hip joint function and stability, and its thickness is closely associated with certain medical conditions, surgical outcomes, and rehabilitation treatments.
Guanying Gao, Huaan Fang, Kaicheng Zhou, Zizhi Mo, Jiayang Liu, Lingyu Meng, Jianquan Wang, Yan Xu   +7 more
doaj   +1 more source

Functional Outcomes of Arthroscopic Combined Anterior Cruciate Ligament Reconstruction and Meniscal Repair: A Retrospective Analysis

Arthroscopy, Sports Medicine, and Rehabilitation, 2020
Purpose: To evaluate the outcomes of arthroscopic meniscal repair performed in combination with anterior cruciate ligament (ACL) repair. Methods: This study presents a case series of 34 patients who underwent repair of meniscal tears along with ACL ...
Shirish Pathak, M.S., Abhinav Bharadwaj, M.S., Prateek Patil, M.S., Sudarshan Raut, M.S., Srikanth RV, M.S.   +4 more
doaj   +1 more source

A new classification of talocalcaneal coalitions based on computed tomography for operative planning

BMC Musculoskeletal Disorders, 2021
Background Current classifications emphasize the morphology of the coalition, however, subtalar joint facets involved should also be emphasized. Objective The objective of this study was to develop a new classification system based on the articular ...
Anhong Wang, Weili Shi, Lixiang Gao, Linxin Chen, Xing Xie, Feng Zhao, Yanbin Pi, Chen Jiao, Yuelin Hu, Dong Jiang, Qinwei Guo   +10 more
doaj   +1 more source