Results 171 to 180 of about 927,389 (334)

An artificial intelligence-driven revolution in orthopedic surgery and sports medicine

Jingqi Guan, Zuhao Li, Shihao Sheng, Qiushui Lin, S. Wang, Dongliang Wang, Xiao Chen, Jiacan Su   +7 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Large Language Model-Based Writing in Published Sports Medicine Research: Uncovering a Growing Influence. [PDF]

Orthop J Sports Med
Nassar JE, Farias MJ, Singh M, Dinh PV, Sahhar M, Daher M, Fallon R, Marcaccio SE, Daniels AH, Owens BD.   +9 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Analysis of the Distribution of Private Research Funding to Sports Medicine Orthopaedic Surgeons. [PDF]

Orthop J Sports Med
Shah AK, Shah IK, Burkhart RJ, Gould HP, Calcei JG, Strickland SM, Voos JE.   +6 more
europepmc   +1 more source

The Brazilian Society of Cardiology and Brazilian Society of Exercise and Sports Medicine Updated Guidelines for Sports and Exercise Cardiology - 2019 [PDF]

, 2019
Nabil Ghorayeb, Ricardo Stein, Daniel Jogaib Daher, Anderson Donelli da Silveira, Luiz Eduardo Fonteles Ritt, Daniel Fernando Pellegrino dos Santos, Ana Sierra, Artur Haddad Herdy, Cláudio Gil Soares de Araújo, Cléa Simone Sabino de Souza Colombo, Daniel Arkader Kopiler, Filipe Ferrari Ribeiro de Lacerda, José Kawazoe Lazzoli, Luciana Diniz Nagem Janot de Matos, Marcelo Bichels Leitão, Ricardo Contesini Francisco, Rodrigo Otávio Bougleux Alô, Sérgio Timerman, Tales de Carvalho, Thiago Ghorayeb Garcia   +19 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Letter to the editor regarding: "challenges confronted by pediatricians in evaluation of Pediatric athletes: awareness on Pediatric Sports Medicine". [PDF]

Ann Med
Türe E, Özkaya AK.
europepmc   +1 more source

Analysing recurrent events in exercise science and sports medicine

, 2010
Ian Cook
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source