Results 61 to 70 of about 358,543 (289)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Sports Medicine & Fitness News (1985 Fall)
, 1985 Sports Medicine Fitness Center. (1985). Sports Medicine & Fitness News (1985 Fall).
Sports Medicine Fitness Center
core
In Response to COVID-19: Current Trends in Orthopaedic Surgery Sports Medicine Fellowships.
, 2021 BackgroundThe COVID-19 (SARS-COV-2) pandemic has brought unprecedented challenges to the health care system and education models. The reduction in case volume, transition to remote learning, lack of sports coverage opportunities, and decreased clinical ...
Dugas, Jeffrey R +8 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sports Medicine & Fitness News (1986 Summer)
, 1986 Sports Medicine Fitness Center. (1986). Sports Medicine & Fitness News (1986 Summer).
Sports Medicine Fitness Center
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Sports Medicine & Fitness News (1983-01 and 02)
, 1983 Sports Medicine Fitness Center. (1983). Sports Medicine & Fitness News (1983-01 and 02).
Sports Medicine Fitness Center
core
Ethical dilemmas faced by the team physician : overlooked in sports medicine education?
, 2014 The authors reflect on the ethical issues facing team physicians in soccer. They argue that sports ethics may have been overlooked in sports medicine education.
Börjesson, Mats,, Karlsson, Jon
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Sports Medicine & Fitness News (1984-01 and 02)
, 1984 Sports Medicine Fitness Center. (1984). Sports Medicine & Fitness News (1984-01 and 02).
Sports Medicine Fitness Center
core