Objective Lactate is increasingly recognized as an energy substrate, but its relevance to amyotrophic lateral sclerosis (ALS) remains unclear. We examined whether blood lactate is associated with survival and weight loss in ALS. Methods This retrospective study included an Australian exploratory cohort and a Japanese validation cohort with clinical ...
Ryutaro Nakamura +8 more
wiley +1 more source
Recent Trends in Metabolomics by NMR Spectroscopy
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco +6 more
wiley +2 more sources
Knowledge Gaps, Sleep Disturbances, and Energy Imbalance Among Female Field Hockey Players. [PDF]
Puchalt-Urbano X +8 more
europepmc +1 more source
Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study
Objective The prodromal phase of amyotrophic lateral sclerosis (ALS) is poorly defined. We aimed to characterize prescription drug use patterns in the pre‐diagnostic period by analyzing nationwide prescription data to identify the earliest divergence between individuals who developed ALS and matched healthy controls.
Magne Haugland Solheim +6 more
wiley +1 more source
Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral +52 more
wiley +1 more source
Motor coordination in school-aged children with different nutritional statuses following a non-immersive virtual reality intervention. [PDF]
Da Silva Souza AP +12 more
europepmc +1 more source
Orally administered polystyrene microplastics accumulate in murine tissues and are detected using MALDI‐MSI with TIMS. Lipid profiling reveals decreases in hexosylceramides, sphingomyelins, and ether‐linked phospholipids, indicating altered metabolism.
Karina A. Vargas +5 more
wiley +1 more source
Family Eating Habits and Dietary Quality of Spanish Children and Adolescents: The PASOS Study. [PDF]
Ródenas-Munar M +28 more
europepmc +1 more source
Associations Between Nutritional Intake, Body Composition, Menstrual Health, and Performance in Elite Female Trail Runners. [PDF]
Piñol-Granadino N +7 more
europepmc +1 more source
Differences in Cardiovascular, Biochemical and Nutritional Parameters Between High- and Low-Altitude Winter Sports Athletes. [PDF]
Jimenez-Casquet MJ +3 more
europepmc +1 more source

