Results 131 to 140 of about 825,896 (353)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Cardiac Evaluation of the Children Before Participation of Sports Activities

, 2021
Hüseyin Yılmaz, Fatih Şap
openalex   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

In the perception of the Olympic movement and gender equity in sport, are gender and sport practice determining factors?

Frontiers in Sports and Active Living
BackgroundThe Olympic Movement (OM) has evolved considerably, with the modern Olympic Games as its main emblem in the world. Within its most recent agenda, issues such as sustainability, fair play, however, inclusion and gender equity have gained greater
Hussein Muñoz-Helú, Luis Felipe Reynoso-Sánchez, Karla Noelia Cruz-Morales, Ciria Margarita Salazar-C, Leonardo Jose Mataruna-Dos-Santos   +4 more
doaj   +1 more source

Survey on the Availability of Facilities and Infrastructure and Active Participation of Physical Education, Sports and Health Teachers in Teacher Deliberation (MGMP) on Their Performance and Professional Competence at Junior High Schools in Sorong City

, 2023
La Robi, Agus Sumhendartin Suryobroto, Abdul Alim, Delano Wisnu, Wahyu Dwi Yulianto   +4 more
openalex   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Girls play basketball too? A study of the mechanisms of traditional social gender consciousness on female participation in contact leisure sports

Frontiers in Psychology
BackgroundWith the development of women’s sports, the mechanism of barriers to women’s leisure sports participation has attracted extensive attention from the academic community.
Yushan He, Guibin Su, Guibin Su, Lujuan Wang, Haonan Qian   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Does participation in extracurricular activities reduce engagement in risky behaviours? [PDF]

This study finds that participation in extracurricular activities significantly reduces engagement in risky behaviours among Australian adolescents. However, the effects differ by activity type, gender and to some extent by socio-economic status (SES ...
Trinh Le
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