Results 151 to 160 of about 246,734 (314)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Gym and Fitness Injuries amongst those Aged 16–64 in New Zealand: Analysis of Ten Years of Accident Compensation Corporation Injury Claim Data

Sports Medicine - Open
Background To provide epidemiological data for minor and moderate-to-serious injury claims for gym and fitness related injuries amongst those aged 16–64 in New Zealand, to inform the development of an injury prevention program.
Melissa Cuthbertson-Moon, Patria A. Hume, Hannah E. Wyatt, Isaac Carlson, Bryce Hastings   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

An ethnographic enquiry into the use of sports science and technologies in professional rugby. [PDF]

, 2012
Sports Science and Sports Medicine are becoming an inherent part of the landscape of high performance sports environments. Such is their visibility, that there are currently over 25,000 students training as sports scientists alone; a number greater than ...
BAKER, CATHERINE,ELIZABETH
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Efeito agudo da técnica de autoliberação miofascial aplicada nos agonistas e antagonistas sobre o desempenho de repetições máximas, tempo sob tensão e percepção subjetiva de esforço na cadeira extensora

Revista Brasileira de Prescrição e Fisiologia do Exercício, 2017
Objetivo: Verificar o efeito da técnica de auto liberação miofascial (ALMF) aplicada nos músculos agonistas e antagonistas sobre o desempenho repetições máximas, tempo sob tensão (TST), índice de fadiga (IF) e percepção subjetiva de esforço (PSE) em ...
Héron Salvini, Michel Antunes, Vicente Pinheiro Lima, Jurandir Baptista da Silva, Haroldo Santana, Gabriel Andrade Paz   +5 more
doaj  

Editorial: Emotions and sport performance

Frontiers in Psychology, 2023
Lael Gershgoren, Jean-Charles Lebeau, Sicong Liu, Gershon Tenenbaum   +3 more
openaire   +3 more sources

Executive Pay Regulation: What Regulators, Shareholders, and Managers Can Learn from Major Sports Leagues [PDF]

Executive pay regulation is widely discussed as a measure to reduce financial mismanagement in corporations. We show that the professional team sports industry, the only industry with substantial experience in the regulation of compensation arrangements,
Markus Lang, Helmut Dietl, Tobias Duschl
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Antitrust Analysis of Sports Leagues

I present an overview of the antitrust literature on sports leagues, with particular emphasis on the National Collegiate Athletic Association, the National Football League, Major League Baseball, the National Basketball Association, and the National ...
Pelnar, Gregory
core