Results 31 to 40 of about 111,954 (307)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Socialization of children with disabilities of various nosological groups by means of physical culture and sports

Вестник Тамбовского университета. Серия: Гуманитарные науки, 2018
Developed and implemented in practice of work of Nizhnevartovsk Municipal Autonomous Extended Education Institution “Youth Sports School” program socialization of children with disabilities by means of physical culture and sports. The aim of the study is
L. E. Savinykh
doaj   +1 more source

The importance of physical activity participation among persons with disabilities

Edu Sportivo, 2022
Participation in physical activity and sports is beneficial for psychosocial health among children and adolescents with a disability. People with disabilities are far less likely to engage in physically active lifestyles than are people without ...
Nagoor Meera Abdullah, Noorasiah Zainal Abidin, Mohamad Rahizam Abdul Rahim, Zarizi Abd Rahman, Novri Gazali   +4 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Disabled sports and physiological specificity in persons with spinal cord injury

The Journal of Physical Fitness and Sports Medicine, 2014
Today, a large proportion of persons with spinal cord injury (SCI) can return to society thanks to advances in biomedical care. Various sports activities are recommended, especially for wheelchair-bound disabled persons with SCI, in order to maintain proper physical fitness. It is important to know sports activities-induced physiological specificity in
Takeshi Nakamura, Kazunari Furusawa, Ken Kouda, Yukihide Nishimura, Yusuke Sasaki, Yasunori Umemoto, Motohiko Banno, Takahiro Ogawa, Takashi Kawasaki, Tomoyuki Ito, Toshihito Mitsui, Fumihiro Tajima   +11 more
openaire   +3 more sources

Oscar Pistorius and the Future Nature of Olympic, Paralympic, and Other Sports [PDF]

, 2008
Oscar Pistorius is a Paralympic bionic leg runner and record holder in the 100, 200, and 400 meters who wants to compete in the Olympics. This paper provides an analysis of a) his case; b) the impact of his case on the Olympics, the Paralympics and other
Gregor Wolbring
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Designing a Paradigmatic Model for the Development of Sports for Persons with Disabilities in Iraq

دراسات وبحوث التربية الرياضية
This research aims to design a paradigmatic model for the development of sports for persons with disabilities in Iraq using grounded theory. This research is qualitative and aimed at being developmental-applicative.
Najah Abdul Hassan Awfi Al-Shaibawi , Saeid Tabesh , Morteza Dousti, Masoumeh Kalateh Seifari, Taghi Ashouri   +4 more
doaj   +1 more source

Alarming low physical activity levels in Chilean adults with disabilities during COVID-19 pandemic: a representative national survey analysis

Frontiers in Public Health, 2023
BackgroundPeople with disabilities usually face barriers to regularly engaging in physical activities. Estimating physical activity patterns are necessary to elaborate policies and strategies to facilitate active lifestyles, considering the particular ...
Matías Henríquez, Rodrigo Ramirez-Campillo, Carlos Cristi-Montero, Raul Reina, Cristián Alvarez, Gerson Ferrari, Nicolas Aguilar-Farias, Kabir P. Sadarangani, Kabir P. Sadarangani   +8 more
doaj   +1 more source

COMPARISON OF SPORTS SCIENCE STUDENTS ATTITUDES TOWARDS THE EDUCATION OF PERSONS WITH DISABILITIES AND THEIR ATTITUDES TOWARDS INTERNATIONAL SPORTS ORGANIZATIONS

The Online Journal of Recreation and Sport, 2021
The aim of this study is to compare the attitudes of students studying in sports sciences towards education of disabled individuals and towards international sports organizations. The target population of this study, which is carried out by relational screening method, one of the quantitative research designs, consists of students studying at the ...
KISA, CİHAD, Tatar, Suzan Tuğçe, MUSA, MİHRİAY, GÜNEL, İLKER, KEPOĞLU, ABDURRAHMAN   +4 more
openaire   +2 more sources