Results 121 to 130 of about 400,788 (314)
Entertainment and Sports Law JournalCaster Semenya began her legal claim against the International Association of Athletics Federations (IAAF) regarding the discriminatory effect of the the Female Eligibility Regulations in Athletics (the ‘DSD Regulations’) in June 2018.
Jonathan Cooper
doaj +2 more sources
Regulating competitive balance in sport [PDF]
, 2012 Sport is an integral part of popular culture, capturing the hearts and minds of millions of people from every section of society 1. Maintaining competitive balance in sport is essential in preserving its long term survival. A higher uncertainty of outcome in contests is likely to result in greater spectator demand and increased revenues; whereas an ...
openaire
Franklin Sports – Tracking Report – Dominican Republic Factory Code: 12900191362J; October 26 – 27, 2011 [PDF]
, 2011 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The 2010 regulations on golf groove design: impact on ball flight characteristics during a controlled shot. [PDF]
, 2013 The purpose of this study was to investigate the difference in the amount of spin that can be generated during a controlled golf shot, as a result of the 2010 rule change regarding restrictions applied to the design of the grooves on the clubface ...
Burnham, Paul +2 more
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Do Labor Intensive Industries Generate Employment? Evidence from firm level survey in India [PDF]
This study attempts to address the issue of declining labour intensity in Indias organized manufacturing in order to understand the constraints on employment generation in the labour intensive sectors.
Deb Kusum Das, Gunajit Kalita
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source