Results 111 to 120 of about 1,970,120 (380)
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Las elecciones presidenciales del 2006 a través de los spots de campaña
Las campañas electorales por la presidencia de la República han propiciado un intenso debate en torno al sistema político mexicano. Uno de los temas que han adquirido mayor visibilidad es el de publicidad política en televisión. Ilustrado por los spots
Julio Juárez Gámiz
doaj
Prevalence of Blue Spot among Mongolian Newborn Infants
Objectives: The aim of this study was to determine the prevalence and characteristics of Mongolian spots in Mongolian infants. Methods: This hospital-based, descriptive cross-sectional study was conducted nationwide among 2641 newborn infants in ...
Suvd Batbaatar+5 more
doaj +1 more source
Reversed-polarity regions [PDF]
The 58 RPRS studied have a lifespan comparable to normal active regions and have no tendency to rotate toward a more normal alignment. They seem to have stable configurations with no apparent evidence suggesting stress due to their anomalous magnetic ...
Tang, F.
core +1 more source
Large scale flow around turbulent spots
Numerical simulations of a model of plane Couette flow focusing on its in-plane spatio-temporal properties are used to study the dynamics of turbulent spots.Comment: 16 pages, 6 ...
Emmons H. W.+5 more
core +3 more sources
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
wiley +1 more source
Background Systematic mutagenesis studies have shown that only a few interface residues termed hot spots contribute significantly to the binding free energy of protein-protein interactions.
Wang Yong+6 more
doaj +1 more source