Results 111 to 120 of about 2,010,547 (381)
Evidence, Experts and Systematic Reviews. Has COVID-19 changed their importance?
Ricardo Maia Ferreira
doaj +1 more source
Single molecule surface enhanced Raman scattering (SM-SERS) is a highly local effect occurring at sharp edges, interparticle junctions and crevices or other geometries with a sharp nanoroughness of plasmonic nanostructures ("hot spots").
D. Radziuk, H. Moehwald
semanticscholar +1 more source
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
wiley +1 more source
Prevalence of Blue Spot among Mongolian Newborn Infants
Objectives: The aim of this study was to determine the prevalence and characteristics of Mongolian spots in Mongolian infants. Methods: This hospital-based, descriptive cross-sectional study was conducted nationwide among 2641 newborn infants in ...
Suvd Batbaatar+5 more
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Las elecciones presidenciales del 2006 a través de los spots de campaña
Las campañas electorales por la presidencia de la República han propiciado un intenso debate en torno al sistema político mexicano. Uno de los temas que han adquirido mayor visibilidad es el de publicidad política en televisión. Ilustrado por los spots
Julio Juárez Gámiz
doaj
Three-Fold Diffraction Symmetry in Epitaxial Graphene and the SiC Substrate
The crystallographic symmetries and spatial distribution of stacking domains in graphene films on SiC have been studied by low energy electron diffraction (LEED) and dark field imaging in a low energy electron microscope (LEEM). We find that the graphene
Gabaly, Farid El+5 more
core +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
Background Systematic mutagenesis studies have shown that only a few interface residues termed hot spots contribute significantly to the binding free energy of protein-protein interactions.
Wang Yong+6 more
doaj +1 more source