Results 131 to 140 of about 2,094,155 (381)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Dark Matter Blind Spots at One-Loop

open access: yes, 2019
We evaluate the impact of one-loop electroweak corrections to the spin-independent dark matter (DM) scattering cross-section with nucleons ($\sigma_{\rm SI}$), in models with a so-called blind spot for direct detection, where the leading-order prediction
Han, Tao   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Dimensionless Normalized Wave Power in the Hot-spot Areas of the Black Sea [PDF]

open access: diamond, 2020
Ajab Gul Majidi   +3 more
openalex   +1 more source

The evolutionary turnover of recombination hot spots contributes to speciation in mice

open access: yesGenes & Development, 2016
In this study, Smagulova et al investigate how the speciation gene in mammals, Prdm9, regulates hot spots of genetic recombination and how this contributes to speciation.
F. Smagulova   +4 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Comunicação governamental nos spots sonoros - o caso brasileiro

open access: yesMás Poder Local
Neste artigo apresentamos um mapeamento dos spots produzidos pelos ministérios no primeiro ano de governo Lula (PT), com a sua segunda reeleição, em 2022.
Luciana Panke   +2 more
doaj  

Rigorous assessment and integration of the sequence and structure based features to predict hot spots

open access: yesBMC Bioinformatics, 2011
Background Systematic mutagenesis studies have shown that only a few interface residues termed hot spots contribute significantly to the binding free energy of protein-protein interactions.
Wang Yong   +6 more
doaj   +1 more source

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