Results 131 to 140 of about 2,010,547 (381)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Comunicação governamental nos spots sonoros - o caso brasileiro

open access: yesMás Poder Local
Neste artigo apresentamos um mapeamento dos spots produzidos pelos ministérios no primeiro ano de governo Lula (PT), com a sua segunda reeleição, em 2022.
Luciana Panke   +2 more
doaj  

Using the Sun to estimate Earth-like planets detection capabilities.I. Impact of cold spots

open access: yes, 2010
Stellar spots may in some cases produce radial velocity (RV) signatures similar to those of exoplanets. To further investigate the impact of spots, we aim at studying the detectability of Earth mass planets in the habitable zone (HZ) of solar type stars,
Desort, M.   +2 more
core   +1 more source

Vulnerability to climate change in three hot spots in Africa and Asia: key issues for policy-relevant adaptation and resilience-building research

open access: yesRegional Environmental Change, 2015
Providing sound evidence to inform decision-making that considers the needs of the most vulnerable to climate change will help both adaptation and development efforts.
K. Souza   +5 more
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Time evolution and rotation of starspots on CoRoT-2 from the modelling of transit photometry

open access: yes, 2011
CoRoT-2, the second planet-hosting star discovered by the CoRoT satellite, is a young and active star. A total of 77 transits were observed for this system over a period of 135 days.
Lanza, A. F., Silva-Valio, Adriana
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

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