Results 151 to 160 of about 2,010,547 (381)

Research on the Evaluation and Optimization of Street Quality in Cultural Attractions Based on Spatial Data

open access: yesISPRS International Journal of Geo-Information
Historic and cultural scenic spots are concentrated spaces that hold historic and cultural value for a city, and their streets form the foundation of their scenery.
Chao Chen, Suyoung Kim
doaj   +1 more source

Population hot spots and cold spots in regional Australia: socio-economic patterns [PDF]

open access: yes
It is well known that regional differences exist in the distribution of population growth and decline and that these patterns are associated with differing patterns of socio-economic performance.
Baum, Scott
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Mongolian spots

open access: yesIndian Journal of Paediatric Dermatology, 2021
Neha Sud, Resham Vasani
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Lactobacillus plantarum , the Cause of “Yeast Spots” on Olives [PDF]

open access: gold, 1953
Reese H. Vaughn   +5 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Identifying Conservation Priority Areas of Hydrological Ecosystem Service Using Hot and Cold Spot Analysis at Watershed Scale

open access: yesRemote Sensing
Hydrological Ecosystem Services (HES) are crucial components of environmental sustainability and provide indispensable benefits. The present study identifies critical hot and cold spots areas of HES in the Aglar watershed of the Indian Himalayan Region ...
Srishti Gwal   +3 more
doaj   +1 more source

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