Results 171 to 180 of about 1,970,120 (380)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

SPOT the DIAGNOSIS [PDF]

open access: yesEuropean Heart Journal. Acute Cardiovascular Care, 2021
David A. Morrow   +3 more
openaire   +5 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Routing Optimization for Large-Scale Inspection-Maintenance of EV Charging Spots With Multiple Types of Personnel and Composite Customer Satisfaction: A Multi-Stage Approach

open access: yesIEEE Access
Electric vehicle (EV) charging spots require frequent inspections to identify potential safety hazards, and charging piles in charging spots exhibit a significant failure rate, necessitating maintenance.
Meng Zhang, Lulu Sun, Qi Jiang, Wei Cui
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Bright spots among the world’s coral reefs

open access: yesNature, 2016
J. Cinner   +38 more
semanticscholar   +1 more source

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