Results 201 to 210 of about 2,094,155 (381)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Investigation of Methacryloyl-Modified Gelatin-Based Hydrogels for Inkjet-Printed Biosensors and Their Adherence to Polyethylene Terephthalate and Oriented Polypropylene Substrates. [PDF]

Eng Life Sci
Trust CM, Lehmann RM, Schmidt S, Singer V, Baum D, McBeth C, Weber A.   +6 more
europepmc   +1 more source

Numerical investigation of Refill Friction Stir Spot Welding joints [PDF]

, 2015
Anna Derlatka, P. Lacki
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Effective elimination of Moiré fringe at the nanoprecipitate/matrix interface. [PDF]

Appl Microsc
Heo YU, Lee D, Trang TTT, Hong C.
europepmc   +1 more source

Fabrication of precise superhydophilic spots on superhydrophobic surface using laser process and green post process for biomedical application

Doo-Man Chun, Bappy, Mohammad Imran, Chung-Soo Kim   +2 more
openalex   +1 more source

Spot Date 2749

, 2021

openalex   +1 more source

Spotted hyenas [PDF]

Current Biology, 2006
openaire   +2 more sources

Bier spots [PDF]

Canadian Medical Association Journal, 2012
Fang-Yih, Liaw, Chien-Ping, Chiang
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source