Results 61 to 70 of about 2,010,547 (381)
Prediction of binding hot spot residues by using structural and evolutionary parameters
Genetics and Molecular Biology, 2009 In this work, we present a method for predicting hot spot residues by using a set of structural and evolutionary parameters. Unlike previous studies, we use a set of parameters which do not depend on the structure of the protein in complex, so that the ...
Roberto Hiroshi Higa, Clésio Luis Tozzi
doaj +1 more source
Tuning the polarization states of optical spots at the nanoscale on the poincar´e sphere using a plasmonic nanoantenna [PDF]
, 2010 It is shown that the polarization states of optical spots at the nanoscale can be manipulated to various points on the Poincar´e sphere using a plasmonic nanoantenna.
A. Drezet +19 more
core +2 more sources
Bright spots : seeds of a good Anthropocene
, 2016 The scale, rate, and intensity of humans’ environmental impact has engendered broad discussion about how to find plausible pathways of development that hold the most promise for fostering a better future in the Anthropocene.
E. Bennett +21 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Creation of magnetic spots at the neutron star surface [PDF]
, 2014 According to the partially screened gap scenario, an efficient electron-positron pair creation, a general precondition of radio-pulsar activity, relies on the existence of magnetic spots, i.e., local concentrations of strong and small scale magnetic ...
Geppert, U., Viganò, D.
core +2 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Hot spots and the hollowness of proton-proton interactions at high energies
, 2016 We present a dynamical explanation of the hollowness effect observed in proton-proton scattering at $\sqrt s\!=\!7$ TeV. This phenomenon, not observed at lower energies, consists in a depletion of the inelasticity density at zero impact parameter of the ...
Albacete, Javier L., Soto-Ontoso, Alba
core +2 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Interferometry of chemically peculiar stars: theoretical predictions vs. modern observing facilities
, 2014 By means of numerical experiments we explore the application of interferometry to the detection and characterization of abundance spots in chemically peculiar (CP) stars using the brightest star eps~Uma as a case study.
Causi, G. Li +4 more
core +2 more sources
First solar butterfly diagram from Schwabe's observations in 1825-1867 [PDF]
, 2010 The original sunspot observations by Heinrich Samuel Schwabe of 1825-1867 were digitized and a first subset of spots was measured. In this initial project, we determined more than 14 000 sunspot positions and areas comprising about 11% of the total ...
Anastasia Abdolvand +4 more
core +1 more source