Results 81 to 90 of about 129,307 (335)
Advanced Science, EarlyView.Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun +14 more
wiley +1 more source
Non-structural proteins of arthropod-borne bunyaviruses: roles and functions [PDF]
, 2013 Viruses within the Bunyaviridae family are tri-segmented, negative-stranded RNA viruses. The family includes several emerging and re-emerging viruses of humans, animals and plants, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus ...
Alain Kohl +17 more
core +3 more sources
Genetic Diagnosis and Discovery Enabled by Large Language Models
Advanced Science, EarlyView.We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu +25 more
wiley +1 more source
Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages [PDF]
, 2018 Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole ...
Clemente, Tatiana M. +5 more
core +1 more source
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Advanced Science, EarlyView.Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Rickettsias del grupo de las fiebres manchadas en garrapatas del género Amblyomma, capaces de infestar humanos, en áreas rurales del noroeste de Argentina [PDF]
, 2015 This work was performed to detect Rickettsia species of the spotted fever group in Amblyomma ticks likely to infest humans in rural areas from northwestern Argentina.
Nava, Santiago +2 more
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Serious Bacterial Infections Acquired During Treatment of Patients Given a Diagnosis of Chronic Lyme Disease - United States. [PDF]
, 2017 The term "chronic Lyme disease" is used by some health care providers as a diagnosis for various constitutional, musculoskeletal, and neuropsychiatric symptoms (1,2).
Blackburn, Brian G +9 more
core +1 more source
SPOTTED FEVER GROUP RICKETTSIA IN DOGS IN JAPAN
Japanese Journal of Medical Science and Biology, 1989 Prevalence of antibody against spotted fever group-rickettsia in dogs (14/134) from the northern part of Shikoku Island, where spotted fever group rickettsia infection in human is endemic, is significantly higher than that in dogs (4/189) from nonendemic areas.
C, Morita +5 more
openaire +3 more sources
Advanced NanoBiomed Research, EarlyView.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
A contribution to a knowledge of Canadian ticks [PDF]
, 2008 During recent years our knowledge of the biology and distribution of the ticks has greatly increased owing to the discovery of the economic importance of this group as carriers of certain serious diseases to man and domesticated animals. In North America
Hewitt, Charles Gordon
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