Results 131 to 140 of about 488,199 (315)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Parents, Spouses, Children: The Use of Language in the Noble Families of Lithuanian Intellectuals (the Late Nineteenth-Early Twentieth Century)

, 2018
Olga Mastianica-Stankevič
openalex   +2 more sources

The Online Learning Environment: Creating a space for Mauritian women learners

International Review of Research in Open and Distributed Learning, 2005
This paper examines how online distance education acts to democratize access to, and suit the ontologies of, Mauritian women who seek to empower themselves for development.
Sushita Gokool-Ramdoo
doaj  

Understanding the marital self-disclosure experience during chemotherapy for gastric cancer: a qualitative study

Frontiers in Psychology
ObjectiveThis study explores the experiences of Chinese gastric cancer patients and their spouses in implementing marital self-disclosure and examines the barriers and facilitators to the acceptance of marital self-disclosure among gastric cancer ...
Ye Zhou, Ye Zhou, Chong Chin Che, Mei Chan Chong, Haiyan Zhao, Yuzhu Hou, Min Zhao   +6 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Happiness Dynamics with Quarterly Life Event Data [PDF]

This paper addresses the question of when and to what extent individuals are affected by major positive and negative life events, including changes in financial situation, marital status, death of child or spouse and being a victim of crime.
Frijters, Paul, Johnston, David W., Shields, Michael A.   +2 more
core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Internet Access and Internet Purchasing Patterns of Farm Households [PDF]

The Internet is becoming an increasingly important management tool in production agriculture. Using data from the 2004 Agricultural Resource Management Survey (ARMS) and a double-hurdle estimation approach, we explore the adoption of computers with ...
Detre, Joshua D., Mishra, Ashok K., Williams, Robert P.   +2 more
core   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Comparing condom use with different types of partners : evidence from national HIV surveys in Africa [PDF]

Based on nationally representative samples from 13 Sub-Saharan African countries, this paper reinforces and expands previous findings that condom use in general is low in this region, men report using condoms more frequently than women, and unmarried ...
de Walque, Damien, Kline, Rachel
core