Results 141 to 150 of about 488,199 (315)

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Basic Arkansas Intestate Succession, Rights of Surviving Spouses, and Related Curative Techniques for Lawyers and Landmen [PDF]

open access: yes, 2009
Mineral interests may lay dormant for decades before becoming productive. In the interim, however, the owners of these interests do not lay dormant. They live long lives, marry, have children, and eventually, they die.
Robinette, J. Mark, Jr.
core   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Social Security, Pensions and Retirement Behavior Within the Family [PDF]

open access: yes
This paper further extends our efforts to understand how household decisionmaking works and the relation of decisions made within the household to incentives from Social Security and pensions.
Alan L. Gustman, Thomas L. Steinmeier
core  

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Health status and retirement decisison for older european couples. [PDF]

open access: yes
In this paper we use data the European Community Household Panel (ECHP) to describe and analyse the dynamics of joint labour force behaviour of older couples for the EUI2 countries. We focus on three main issues: the relanvance of joint retirement across
Jiménez-Martín, Sergi   +2 more
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Research progress on cancer patients caregiver demands assessment tools

open access: yesHuli yanjiu, 2017
It reviewed the more commonly used selfassessment tools for caregivers of cancer patients,such as The Cancer Survivors’ Partners Unmet Needs Scale(CaSPUN),The Cancer Support Person’s Unmet Needs Survey(SPUNS),The Supportive Care Needs SurveyPartners and ...
GAO Mingxia, Song Huan, LIU Weihua
doaj  

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