Results 41 to 50 of about 488,199 (315)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Nuances of reproductive decisions by women in a rural community of Lagos, Nigeria
INTRODUCTION: Inadequate utilization of maternal health services due to limited reproductive decision-making capacity could be contributory to high maternal mortality in developing countries.
Kikelomo Ololade Wright +5 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Quality of Life of the Spouses of War Related Amputees of Hamedan City, Iran
Aims: Care of the veterans with amputations results in some physical and mental side-effects, mainly, in their spouses, affecting their quality of life.
A. Naderi +5 more
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Retirement and Survivor Annuities for Former Spouses of Federal Employees [PDF]
[Excerpt] A former spouse of a federal employee may be entitled to a share of the employee’s retirement annuity under the Civil Service Retirement System (CSRS) or the Federal Employees’ Retirement System (FERS) if this has been authorized by a state ...
Purcell, Patrick
core +1 more source
Does a Spouse Slow You Down? Marriage and Graduate Student Outcomes [PDF]
Using data on 11,000 graduate students from 100 departments over a 20 year period, I test whether graduate student outcomes (graduation rates, time to degree, publication success, and initial job placement) differ based on a student’s gender and marital ...
Price, Joseph
core +2 more sources
Bingjie Shen, Tianjia Guan, Xinyu Du, Chenyang Pei, Jinhong Zhao, Yuanli Liu School of Health Policy and Management, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of ChinaCorrespondence: Yuanli Liu, School
Shen B +5 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An investigation of loneliness and related factors among the spouses of personnel deployed to long-term naval missions [PDF]
Background: Given the important effects of loneliness on health and it has not been studied precisely in our country among the spouses of personnel deployed to long-term missions, therefore, the current study was done to investigate loneliness and ...
M Amidi Mazaheri +3 more
doaj

