Results 101 to 110 of about 64,115 (267)

Latent profile analysis and influencing factors of dyadic coping in pregnant women with infectious diseases and their spouses

open access: yesHuli yanjiu
ObjectiveTo explore the heterogeneity and influencing factors of the dyadic coping levels of pregnant women with infectious diseases and their spouses.MethodsA total of 201 pairs of pregnant women with infectious diseases and their spouses were surveyed ...
WEI Tao   +5 more
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Young Spouses' Experiences of Having a Partner With Heart Disease and Adolescents Living at Home

open access: yesHealth Expectations
Aim To describe the life situation of spouses having a partner with heart disease and adolescents living at home. Design Qualitative inductive design. Method Participants (n = 22) were included from three Scandinavian countries.
Matilda Holmbom   +7 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Correlation between Resilience and Mental Health with Lifestyle and Parenting Styles of Veterans\' Spouses A Case Study of Ardakan City

open access: yesطب جانباز, 2019
Aims: The physical and mental problems that exist among the veterans have the greatest impact on their spouses, which affects the whole family. The aim of the present study was to investigate the correlation between lifestyle and parenting style with ...
M. Abedini Baltork, F.S. Mir Shamsi
doaj  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Factors Affecting Rumination among Women Having Marital Conflicts

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2017
Aim and Background: Rumination can cause various kinds of damage to which women are more vulnerable. Therefore, the aim of this study was to determine the factors affecting rumination among women having marital conflicts.
فهیمه نامدارپور   +3 more
doaj  

Home - About - Disclaimer - Privacy