Results 301 to 310 of about 441,888 (380)

Time‐ and dose‐related pathological changes in knee osteoarthritis rat model induced by monosodium iodoacetate

Animal Models and Experimental Medicine, EarlyView.
Time‐ and dose‐related pathological changes of knee osteoarthritis rat model induced by monosodium iodoacetate. Abstract Knee osteoarthritis (KOA) is a chronic degenerative disease. Monosodium iodoacetate (MIA) induction is the most commonly used therapeutic effect evaluation and mechanism of action research model; we observed a lack of standardization
Wei Pu, Qi Liu, Shuyan Xue, Siyuan Li, Nan Nan, Yang Liu, Huiqin Hao   +6 more
wiley   +1 more source

Hyperbaric Oxygen Promotes Chronic Wound Healing in Sprague-Dawley Rats by Inhibiting Pyroptosis. [PDF]

Physiol Res
Ma H, Wei X, Lin E, Wang Y, Huang J, Wei H.   +5 more
europepmc   +1 more source

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

E5 treatment showing improved health-span and lifespan in old Sprague Dawley rats. [PDF]

Aging Cell
Singh K, Khairnar SI, Sanghavi A, Yadav TT, Gupta N, Arora J, Katcher HL.   +6 more
europepmc   +1 more source

Establishment and evaluation of a novel rat model of the fourth ventricle hemorrhage

Animal Models and Experimental Medicine, EarlyView.
In this study, a novel rat model of fourth ventricle hemorrhage was established via autologous blood injection through the foramen of Magendie. Anesthetized rats were positioned in a stereotaxic apparatus with their heads tilted downward at an angle of approximately 20° relative to the vertical axis.
Chuhua Fu, Aoqi Liu, Yijia He, Fei Li, Zhouyang Jiang, Peiwen Guo, Zhi Chen, Yujie Chen, Hua Feng   +8 more
wiley   +1 more source

Dataset of histone H3K4me2 modified genes in the liver of female Sprague-Dawley rats with chronic antipsychotic drugs of olanzapine or clozapine. [PDF]

Data Brief
Su Y, Lian J, Deng C.
europepmc   +1 more source

Hepatocellular Iron Accumulation and Increased Cell Proliferation in Polychlorinated Biphenyl-Exposed Sprague-Dawley Rats and the Development of Hepatocarcinogenesis

, 2001
John Whysner, C.-X. Wang
openalex   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

Animal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica, Suzana Stanisavljević, Dragica Mićanović, Ivana Stojanović, Đorđe Miljković   +4 more
wiley   +1 more source

Effects of whole brain proton irradiation at conventional or ultra-high dose rate (FLASH), in adult male Sprague Dawley rats. [PDF]

Sci Rep
Williams MT, Regan SL, Fritz AL, Gollaway BM, Mascia AE, Vatner RE, Perentesis JP, Vorhees CV.   +7 more
europepmc   +1 more source

Diosgenin ameliorates silica‐induced tuberculosis in rats

Animal Models and Experimental Medicine, EarlyView.
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu, Selase Ativui, Michael Ofori, George Owusu, Cynthia Amaning Danquah, Paul Poku Sampene Ossei   +5 more
wiley   +1 more source