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Integrating Metabolomics, Histopathology, and Cardiac Marker Analysis to Assess Valsartan's Efficacy in Mitigating Dasatinib-Induced Cardiac Toxicity in Sprague-Dawley Rats. [PDF]

open access: yesDrug Des Devel Ther
Alhazzani K   +12 more
europepmc   +1 more source
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Prostate cancer in a Sprague‐Dawley rat

The Prostate, 1985
AbstractAn adenocarcinoma of the prostate gland developed in one rat of the Lobund Sprague‐Dawley (S‐D) strain, following treatments with testosterone propionate in silastic membranes. The transplanted cells (PA‐SD1) developed local tumors, metastasized through lymphatic channels to the lungs, and induced osteolytic lesions when deposited adjacent to ...
Morris Pollard, Phyllis H. Luckert
openaire   +4 more sources

Leiomyoma of the iris in a Sprague-Dawley rat

Journal of Comparative Pathology, 1987
A leiomyoma of the iris was composed of bundles of spindle-shaped cells with abundant myoglial fibres and represents the first observation of this rare tumour in a rat.
P Duprat, R.A Owen
openaire   +3 more sources

Behavioral heterogeneity in Sprague-Dawley rats

Physiology & Behavior, 1992
Because of consistent individual differences in animal behavior, it is often difficult to interpret experimental data. We therefore attempted to rank Sprague Dawley rats by a hierarchical ascendant clustering technique using data from avoidance conditioning and open-field testing (scores of exploratory activity before, during, and after an ...
M. Curé, J.P. Rolinat
openaire   +3 more sources

Spontaneous Hibernomas in Sprague-Dawley Rats

Toxicologic Pathology, 2009
Hibernomas are rare neoplasms originating in brown adipose tissue of humans and other animal species, including laboratory animals. Background incidence values for these tumors in all common strains of laboratory rats are generally accepted as being <0.1%.
Richard H. Bruner   +10 more
openaire   +3 more sources

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