Results 91 to 100 of about 781,749 (234)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Behavior of topside and bottomside spread F at equatorial latitudes [PDF]

open access: yes
Diurnal variation of topside and bottomside spread-F and geomagnetic effects from Alouette I ...
Krishnamurthy, B. V.
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Deep learning for face detection using matlab [PDF]

open access: yes, 2020
This project report presents face detection using Convolutional Neural Network algorithm and Deep Learning combination (DCT / DL) throughout MATLAB simulation and modeling.
Slim, Salim Adnan
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Plasma Dynamics Associated With Equatorial Ionospheric Irregularities

open access: yesGeophysical Research Letters, 2018
The Communication/Navigation Outage Forecasting System satellite was operational from 2008, a period of deep solar minimum, to 2015, a period of moderate solar conditions.
Jonathon Matthew Smith, R. A. Heelis
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Interaction of plasma drifts: A hypothesis for equatorial spread F occurrence

open access: yesJournal of Space Weather and Space Climate
Studies on the generation mechanisms of post-sunset ionospheric irregularities, which constitute a threat to trans-ionospheric radio propagation, particularly at the African sector, are quite sparse.
Oyeyemi Elijah Oyedola   +5 more
doaj   +1 more source

Hydrogen ions [PDF]

open access: yes, 1965
Hydrogen ion production and distribution in upper ...
Bauer, S. J.
core   +1 more source

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