Results 101 to 110 of about 781,821 (303)

Plasma Dynamics Associated With Equatorial Ionospheric Irregularities

open access: yesGeophysical Research Letters, 2018
The Communication/Navigation Outage Forecasting System satellite was operational from 2008, a period of deep solar minimum, to 2015, a period of moderate solar conditions.
Jonathon Matthew Smith, R. A. Heelis
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Deep learning for face detection using matlab [PDF]

open access: yes, 2020
This project report presents face detection using Convolutional Neural Network algorithm and Deep Learning combination (DCT / DL) throughout MATLAB simulation and modeling.
Slim, Salim Adnan
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Interaction of plasma drifts: A hypothesis for equatorial spread F occurrence

open access: yesJournal of Space Weather and Space Climate
Studies on the generation mechanisms of post-sunset ionospheric irregularities, which constitute a threat to trans-ionospheric radio propagation, particularly at the African sector, are quite sparse.
Oyeyemi Elijah Oyedola   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Three-Dimensional Numerical Simulations of Equatorial Spread F: Results and Observations in the Pacific Sector [PDF]

open access: yes
A three-dimensional numerical simulation of plasma density irregularities in the postsunset equatorial F region ionosphere leading to equatorial spread F (ESF) is described.
Aveiro, H. C.   +7 more
core   +1 more source

Hydrogen ions [PDF]

open access: yes, 1965
Hydrogen ion production and distribution in upper ...
Bauer, S. J.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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