Results 221 to 230 of about 1,625,584 (294)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Rapid Spread of Novel Infectious Bursal Disease Virus Variant (Genotype A2dB1b) in the Near East and Persian Gulf Regions: Molecular Surveillance and Phylodynamic Reconstruction. [PDF]

Transbound Emerg Dis
Poletto F, Alam S, Cherfane A, Franzo G, Tucciarone CM, Cecchinato M, Legnardi M.   +6 more
europepmc   +1 more source

Reducing spread of neural activation using focused multipolar retinal electrical stimulation in sighted and blinded cats

, 2017
Thomas C. Spencer, James B. Fallon, Carla J. Abbott, Penny J. Allen, Alice Brandli, Chi D. Luu, Mohit N. Shivdasani   +6 more
openalex   +1 more source

Coupled Human-Environment Dynamics of Forest Pest Spread and Control in a Multi-Patch, Stochastic Setting

, 2015
Qasim Ali, Chris T. Bauch, Madhur Anand
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Historical and current spatiotemporal patterns of wild and vaccine-derived poliovirus spread. [PDF]

Nat Microbiol
Candido DDS, Dellicour S, Cooper LV, Prete CA, Jorgensen D, Uzzell CB, Voorman A, Lyons H, Klapsa D, Majumdar M, Arowolo K, Peak CM, Bandyopadhyay AS, Martin J, Grassly NC, Blake IM.   +15 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Genetic connectivity and admixture zones shape the spread of African swine fever in wild Boar populations in North-western Italy. [PDF]

Sci Rep
Meletiadis A, Garcia-Vozmediano A, Riina MV, Vitale N, Di Nicola MR, Maurella C, Massimino M, Caniglia R, Moroni B, Viani A, Zoppi S, Biagetti M, Beato MS, Goria M, Razzuoli E, Orusa R, Ferrari A, Feliziani F, Dondo A, Bozzetta E, Ru G, Acutis PL.   +21 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Going green from within: correlational insights into the spread of pro-environmental behavior through the lens of organismic integration theory. [PDF]

Front Psychol
Molkenthin M, Christoforakos L, Hassenzahl M, Laschke M.   +3 more
europepmc   +1 more source