Results 91 to 100 of about 3,568,047 (295)

Investigation of the possible relationship between the occurrences of atmospheric gravity waves and equatorial Spread-F. [PDF]

Heliyon, 2023
Olawepo AO, Olagunju OE, Ajani OV.
europepmc   +1 more source

Higgledy-piggledy subspaces and uniform subspace designs [PDF]

, 2014
In this article, we investigate collections of `well-spread-out' projective (and linear) subspaces. Projective $k$-subspaces in $\mathsf{PG}(d,\mathbb{F})$ are in `higgledy-piggledy arrangement' if they meet each projective subspace of co-dimension $k ...
Fancsali, Szabolcs L., Sziklai, Péter
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A model for equatorial explosive spread F

Geophysical Research Letters, 1984
Explosive spread F was first described by Woodman and LaHoz [1976]. In such events the 50 MHz radar signal rises at Jicamarca to 10‐20 db above the noise level within a few milliseconds but then disappears within 100 ms or less. Woodman has suggested that electric fields from thunderstorms might drive a plasma instability which could cause these echoes,
M. C. Kelley, D. T. Farley, E. Kudeki, C. L. Siefring   +3 more
openaire   +1 more source

Differential disease restriction of Moloney and Friend murine leukemia viruses by the mouse Rmcf gene is governed by the viral long terminal repeat. [PDF]

, 1991
Neonatal CxD2 (Rmcfr) and Balb/c (Rmcfs) mice inoculated with Moloney murine leukemia virus (M-MuLV) exhibited approximately equivalent time course and pathology for disease.
Brightman, BK, Fan, H, Li, QX, Trepp, DJ
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

IonoGAN: An Enhanced Model for Forecasting Quiet and Disturbed Ionospheric Features From Predicted Ionograms

Space Weather
Ionograms are radar echo graphs that depict vertical ionospheric density profiles, structures, fluctuations, and irregularities, with the F region represented by F‐trace and Spread‐F features in the graphs.
Chu Qiu, Jinhui Cai, Zheng Wang, Pengdong Gao, Guojun Wang, Quan Qi, Bo Wang, Zhengwei Cheng, Jiankui Shi, Yajun Zhu, Xiao Wang, Kai Ding   +11 more
doaj   +1 more source