Results 91 to 100 of about 1,030,149 (344)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Optimum constrained image restoration filters [PDF]

open access: yes
The filter was developed in Hilbert space by minimizing the radius of gyration of the overall or composite system point-spread function subject to constraints on the radius of gyration of the restoration filter point-spread function, the total noise ...
Mcgillem, C. D., Riemer, T. E.
core   +1 more source

Channel Sounding for the Masses: Low Complexity GNU 802.11b Channel Impulse Response Estimation

open access: yes, 2010
New techniques in cross-layer wireless networks are building demand for ubiquitous channel sounding, that is, the capability to measure channel impulse response (CIR) with any standard wireless network and node.
Firooz, Mohammad H.   +4 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Spread spectrum mobile communication experiment using ETS-V satellite [PDF]

open access: yes
The spread spectrum technique is attractive for application to mobile satellite communications, because of its random access capability, immunity to inter-system interference, and robustness to overloading.
Ikegami, Tetsushi   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Spread spectrum wavelet watermarking system

open access: yes, 2005
Lately attention has been focused on wavelet-based watermarking because of its compatibility with the newly developed JPEG 2000 image compression scheme. The major setback associated with wavelet-based watermarking is its vulnerability to geometric distortion caused by the lack of invariance property of wavelet transform.
Georgakis, Apostolos   +1 more
openaire   +1 more source

Navigation system and method [PDF]

open access: yes, 1984
In a global positioning system (GPS), such as the NAVSTAR/GPS system, wherein the position coordinates of user terminals are obtained by processing multiple signals transmitted by a constellation of orbiting satellites, an acquisition-aiding signal ...
Sennott, J. W., Taylor, R. E.
core   +1 more source

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