Results 201 to 210 of about 1,108,477 (248)

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. [PDF]

Nucleic Acids Res
Kennedy DR, Lemière J, Amine AAA, Martin EW, Tan C, Simental E, Braxton J, Maxwell RA, Al-Sady B.   +8 more
europepmc   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Patients' responses & reflections when receiving news of cancer progression: a qualitative study. [PDF]

BJC Rep
Ten Hove J, Kain D, Galica J, O'Donnell J, Brundage MD.   +4 more
europepmc   +1 more source

From thresholds to trajectories: a perspective on reframing alloimmune risk for computational modeling in solid organ transplantation. [PDF]

Front Immunol
Das R, Hod-Dvorai R.
europepmc   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

Arthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Brain regional susceptibility to tauopathy in individuals at risk for chronic traumatic encephalopathy. [PDF]

Alzheimers Dement
Wiegand TLT, Rubinski A, Jung LB, Franzmeier N, Arciniega H, Ravanfar P, Dewenter A, Alosco ML, Tripodis Y, Su Y, Protas H, Lin AP, Pasternak O, Chen K, Coleman MJ, Bouix S, Adler CH, Balcer LJ, Bernick C, Cummings JL, Stern RA, Reiman EM, Shenton ME, Ewers M, Koerte IK, DIAGNOSE CTE Research Project.   +25 more
europepmc   +1 more source

Not Just a Strategy, But the Heartbeat of Our Work: The Importance of Youth Engagement in Drug-Free Communities Coalitions. [PDF]

J Public Health Manag Pract
Taylor C, Martin J, Cummings W, Jarvis L, Costa O, Hussain A.   +5 more
europepmc   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Vaccinations, Cardiovascular Disease, and Role of the Cardiologist. [PDF]

JACC Adv
Nazir NT.
europepmc   +1 more source