Results 71 to 80 of about 132,512 (244)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Dependence of credit spread and macro-conditions based on an alterable structure model.
PLoS ONE, 2018 The fat-tail financial data and cyclical financial market makes it difficult for the fixed structure model based on Gaussian distribution to characterize the dynamics of corporate bonds spreads. Using a flexible structure model based on generalized error
Yun Xie +3 more
doaj +1 more source
Growing information asymmetries as the cloud spreads
Internet Policy Review, 2013 To the extent that they provide content or information to the public, many cloud operators can be regarded as infomediaries - information intermediaries between users looking for information and the supplier of that information.
Primavera De Filippi
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Next-generation spreads: Emerging trends and innovation
Future FoodsSpreadable foods are a diverse category that has gained attention in recent years. Changes in dietary habits and increasingly busy lifestyles have stimulated demand for convenient, ready-to-use products, while technological advances have enabled the ...
Miloš Županjac +3 more
doaj +1 more source
Aspects of complete uniform spreads in frames
International Journal of Mathematics and Mathematical Sciences, 2002 We give a new notion of a complete uniform spread in terms of a relative kind of uniform local connectedness. Properties of this type of (uniform) connectedness are discussed. It is also shown that our concept of complete spread is equivalent to that of
Hlengani James Siweya
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Investor Sentiment and Speculative Bond Yield Spreads
Foundations of Management, 2019 The valuation of risky debt is central to theoretical and empirical work in corporate finance. Although much is known on the returns and valuation of bonds, there is hardly a consensus on the risk components of the yield spreads.
Turkmen Muldur Gozde +2 more
doaj +1 more source