Results 61 to 70 of about 5,132,390 (317)

Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things [PDF]

Cell, 1998
We thank J. Thorner, J. Lorsch, and D. Herschlag for provocative discussions; J. Abelson, R. Luhrmann, T. Nilsen, and R. Reed for preprints; and G. Chanfreau, C. Collins, A. Frankel, A. Kistler, K. Lynch, S. Rader, B. Raumann, D. Ryan, C. Siebel, J. Wagner, Y. Wang, J.
Staley, Jonathan P, Guthrie, Christine
openaire   +2 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

A Contactless Coupled Pendulum and Piezoelectric Wave Energy Harvester: Model and Experiment

Energies
Wireless monitoring systems for the marine environment are important for rapidly growing subsea developments. The power supply of wireless sensor nodes within the monitoring systems, however, is a major challenge.
Wuwei Feng, Hongya Chen, Qingping Zou, Di Wang, Xiang Luo, Cathal Cummins, Chuanqiang Zhang, Shujie Yang, Yuxiang Su   +8 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Broadband Energy Harvester Using Non-linear Polymer Spring and Electromagnetic/Triboelectric Hybrid Mechanism

Scientific Reports, 2017
Over the years, several approaches have been devised to widen the operating bandwidth, but most of them can only be triggered at high accelerations. In this work, we investigate a broadband energy harvester based on combination of non-linear stiffening ...
Rahul K Gupta, Qiongfeng Shi, Lokesh Dhakar, Tao Wang, C. Heng, Chengkuo Lee   +5 more
semanticscholar   +1 more source

Testing of Wing-Tip Spring Device for Gust Loads Alleviation [PDF]

58th AIAA/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference, 2017
Recent aircraft designs have begun considering higher aspect ratio wings in order to reduce induced drag for improved fuel efficiency. In order to meet airport gate requirements, folding wing-tips have been introduced as a solution to the increased wing-span.
Cheung, R. C M, Castrichini, A., Rezgui, D., Cooper, J. E., Wilson, T.   +4 more
openaire   +3 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source

Predicting therapy response in live tumor cells isolated with the flexible micro spring array device

Cell Cycle, 2013
Cells disseminated from primary epithelial tumors into peripheral blood, called circulating tumor cells (CTCs), can be monitored to assess metastases and to provide a surrogate marker of treatment response.
J. Gallant, Elizabeth M. Matthew, Hairong Cheng, R. Harouaka, Nicholas E. Lamparella, Miriam Kunkel, Zhaohai Yang, Harold A. Harvey, Leah V. Cream, Suresh M. Kumar, G. Robertson, Siyang Zheng, J. Drabick, C. Truica, W. El-Deiry   +14 more
semanticscholar   +1 more source